Christopher Uyeda
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Explore the profile of Christopher Uyeda including associated specialties, affiliations and a list of published articles.
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43
Citations
448
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Recent Articles
1.
Rybak C, Fan C, Sharma P, Uyeda C
J Am Chem Soc
. 2024 Oct;
146(43):29720-29727.
PMID: 39419083
Azoarenes are the largest class of photoswitching molecules, and they have a broad range of applications in photopharmacology and materials science. Azoarenes possessing -substitution often display improved properties, including isomerization...
2.
Liu M, Uyeda C
Angew Chem Int Ed Engl
. 2024 May;
63(29):e202406218.
PMID: 38752878
Transition metal-catalyzed carbene transfer reactions have a century-old history in organic chemistry and are a primary method for the synthesis of cyclopropanes. Much of the work in this field has...
3.
Bishop H, Zhao Q, Uyeda C
J Am Chem Soc
. 2023 Sep;
145(37):20152-20157.
PMID: 37695207
Transition-metal-catalyzed reductive coupling reactions of alkynes and imines are attractive methods for the synthesis of chiral allylic amines. Mechanistically, these reactions involve oxidative cyclization of the alkyne and the imine...
4.
Liu M, Le N, Uyeda C
Angew Chem Int Ed Engl
. 2023 Sep;
62(42):e202308913.
PMID: 37661190
Nickel PyBox catalysts promote nucleophilic cyclopropanation reactions using CH Cl as a methylene source and Mn as a stoichiometric reductant. The substrate scope includes a broad range of alkenes bearing...
5.
Kanale V, Uyeda C
Angew Chem Int Ed Engl
. 2023 Sep;
62(42):e202309681.
PMID: 37656431
Cobalt catalysts promote highly enantioselective ring-opening reactions of 2,5-dihydrofurans using vinylidenes. The products are acyclic organozinc compounds that can be functionalized with an electrophile. The proposed mechanism involves the generation...
6.
Berger K, Martinez R, Zhou J, Uyeda C
J Am Chem Soc
. 2023 Apr;
145(17):9441-9447.
PMID: 37086176
Cyclopropanes are common building blocks in pharmaceuticals, agrochemicals, and organic materials. The most general methods for the synthesis of chiral cyclopropanes are catalytic additions of diazoalkanes to alkenes. However, a...
7.
Rybak C, Andjaba J, Fan C, Zeller M, Uyeda C
Inorg Chem
. 2023 Apr;
62(15):5886-5891.
PMID: 37018479
Azoarenes function as molecular switches that can be triggered by external stimuli, such as heat, light, and electrochemical potential. Here, we show that a dinickel catalyst can induce cis/trans isomerization...
8.
Kalb A, Liu M, Bosso M, Uyeda C
Chem Sci
. 2022 Nov;
13(37):11190-11196.
PMID: 36320482
A dinickel catalyst promotes the [2 + 2 + 1]-cycloaddition of two aldehyde equivalents and a vinylidene. The resulting methylenedioxolane products can be deprotected in one pot under acidic conditions...
9.
Steiman T, Kalb A, Coombs J, Kirkland J, Torres H, Ess D, et al.
ACS Catal
. 2022 Oct;
11(23):14408-14416.
PMID: 36237605
A dinickel catalyst promotes reductive cyclization reactions of 1,1-dichloroalkenes containing pendant olefins. The reactions can be conducted with a Zn reductant or electrocatalytically using a carbon working electrode. Mechanistic studies...
10.
Uyeda C, Kalb A
Chem Catal
. 2022 Jun;
2(4):667-678.
PMID: 35663346
Efforts to develop catalytic carbene transfer reactions have largely relied on the use of diazo precursors. However, diazoalkanes are susceptible to undergoing violent exothermic decomposition unless they contain stabilizing substituents....