Henry N C Wong
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Explore the profile of Henry N C Wong including associated specialties, affiliations and a list of published articles.
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56
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Recent Articles
1.
Wang J, Cheng G, Wong H, Peng X
J Org Chem
. 2025 Feb;
PMID: 39928988
Bicyclo[3.1.0]hexane is a structural motif of the bioactive, naturally occurring cryptotrione and could be realized via a Pt- or Au-catalyzed reaction on 1,5-enyne with good control of the diastereoselectivity. In...
2.
Xu X, Ma H, Cui J, Peng X, Wong H
Chem Sci
. 2025 Feb;
16(10):4342-4351.
PMID: 39911340
Herein we report a novel approach for diversification of tetraphenylene regioselective late-stage iodination followed by atom(s) insertion into the resulting cyclic iodonium salts. Thus, the steric hindrance effect of -butyl...
3.
Chen P, Chen H, Wong H, Peng X
Org Biomol Chem
. 2023 Jul;
21(30):6083-6095.
PMID: 37485859
The advancement of transition-metal-catalyzed coupling reactions has been demonstrated as a highly effective strategy for the formation of carbon-carbon bonds, which serve as the fundamental basis for organic synthetic chemistry....
4.
Huo L, Wang X, Zhang Z, Jia Z, Peng X, Wong H
Chem Sci
. 2023 Feb;
14(6):1342-1362.
PMID: 36794178
Metal-catalysed cross-coupling reactions are amongst the most widely used methods to directly construct new bonds. In this connection, sustainable and practical protocols, especially transition metal-catalysed cross-coupling reactions, have become the...
5.
Guo J, Ma H, Xiong W, Fan L, Zhou Y, Wong H, et al.
Chem Sci
. 2022 Dec;
13(46):13914-13921.
PMID: 36544735
Herein, we report an efficient kinetic resolution of alkyl allylic alcohols enabled by an iridium-catalyzed enantioselective alkynylation of alkyl allylic alcohols with potassium alkynyltrifluoroborates. A wide range of chiral 1,4-enynes...
6.
Guo J, Xiong W, Ma H, Fan L, Zhou Y, Wong H, et al.
Chem Sci
. 2022 Jun;
13(16):4608-4615.
PMID: 35656141
We report herein a novel approach involving optical resolution of (±)-1,16-dihydroxytetraphenylene (DHTP) by chiral gold(iii) complexation. This method features several key advantages, , recyclability of chiral resolution reagents, feasibility of...
7.
Wang J, Li Y, Du J, Huang S, Ding C, Wong H, et al.
Org Lett
. 2022 Feb;
24(7):1561-1565.
PMID: 35157459
Alkynyl esters are viable dipolarophiles for the palladium-catalyzed asymmetric (3 + 2) cycloaddition with vinyl epoxides. The chiral dihydrofurans are obtained in high yields and high values. The use of...
8.
9.
Chen P, Wang Z, Peng X, Wong H
Org Lett
. 2021 May;
23(11):4385-4390.
PMID: 34008404
We present herein an efficient synthetic protocol involving iron-catalyzed cross-coupling of organolithium compounds with vinyl halides as key coupling partners. More than 30 examples were obtained with moderate to good...
10.
Lyu M, Zhong Z, Lo V, Wong H, Peng X
Angew Chem Int Ed Engl
. 2020 Jul;
59(45):19929-19933.
PMID: 32692466
The total synthesis of cryptotrione (1) was enabled by substrate-controlled diastereoselective construction of the bicyclo[3.1.0]hexene framework through platinum-catalyzed enyne cycloisomerization and Lewis acid induced polyene cyclization to construct the abietane-type...