You-Yeon Won
Overview
Explore the profile of You-Yeon Won including associated specialties, affiliations and a list of published articles.
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Articles
64
Citations
673
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0
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Recent Articles
1.
Jun T, Shin S, Won Y
Int J Pharm
. 2024 Aug;
664:124636.
PMID: 39197798
Protein therapeutics, particularly antibodies, depend on maintaining their native structures for optimal function. Hydrophobic interfaces, such as the air-water interface, can trigger protein aggregation and denaturation. While completely avoiding such...
2.
Jo S, Roh S, Shim J, Yu J, Jung Y, Jang W, et al.
Biomacromolecules
. 2024 Jul;
25(8):5374-5386.
PMID: 39014545
Hydrogels are promising materials for biomedical applications, particularly in drug delivery and tissue engineering. This study highlights thermoresponsive hydrogels, specifically poly(lactic--glycolic acid) (PLGA)-poly(ethylene glycol) (PEG)-PLGA triblock copolymers, and introduces a...
3.
Fesenmeier D, Cooper E, Won Y
J Colloid Interface Sci
. 2024 Feb;
661:861-869.
PMID: 38330658
Hypothesis Conventional solvent exchange formulation methods face limitations when trying to control the final non-equilibrium size properties of block copolymer micelles containing a strongly hydrophobicity and a rigid block because...
4.
Fesenmeier D, Kim S, Won Y
Soft Matter
. 2023 Nov;
19(47):9269-9281.
PMID: 38009013
In the pursuit of the development of a first-in-kind polymer lung surfactant (PLS) therapeutic whose effects are biophysical in nature, a comprehensive understanding of the factors affecting the air-water surface...
5.
Kim S, Park S, Fesenmeier D, Won Y
Int J Pharm
. 2023 Oct;
646:123476.
PMID: 37805148
Polymer lung surfactant (PLS) is a polyethylene glycol (PEG)-brushed block copolymer micelle designed for pulmonary surfactant replacement therapy. Saccharides (e.g., sucrose and (2-hydroxypropyl)-β-cyclodextrin) and water-soluble polymers (e.g., PEG), common excipients...
6.
Kim S, Park S, Fesenmeier D, Jun T, Sarkar K, Won Y
Langmuir
. 2023 Sep;
39(38):13546-13559.
PMID: 37706471
Amphiphilic block copolymer micelles can mimic the ability of natural lung surfactant to reduce the air-water interfacial tension close to zero and prevent the Laplace pressure-induced alveolar collapse. In this...
7.
Viswanath D, Park J, Misra R, Pizzuti V, Shin S, Doh J, et al.
Wiley Interdiscip Rev Nanomed Nanobiotechnol
. 2023 Aug;
16(1):e1924.
PMID: 37632203
Rare but consistent reports of abscopal remission in patients challenge the notion that radiotherapy (RT) is a local treatment; radiation-induced cancer cell death can trigger activation and recruitment of dendritic...
8.
Viswanath D, Shin S, Yoo J, Torregrosa-Allen S, Harper H, Cervantes H, et al.
Biomater Sci
. 2023 Aug;
11(18):6311-6324.
PMID: 37552121
Photodynamic therapy (PDT) using 5-aminolevulinic acid (ALA) prodrug is a clinically tried and proven treatment modality for surface-level lesions. However, its use for deep-seated tumors has been limited due to...
9.
Sarkar K, Torregrossa-Allen S, Elzey B, Narayanan S, Langer M, Durm G, et al.
Mol Pharm
. 2023 Jul;
20(8):4331-4334.
PMID: 37477492
No abstract available.
10.
Chang Y, Cai X, Syahirah R, Yao Y, Xu Y, Jin G, et al.
Nat Commun
. 2023 Apr;
14(1):2266.
PMID: 37080958
Glioblastoma (GBM) is one of the most aggressive and lethal solid tumors in human. While efficacious therapeutics, such as emerging chimeric antigen receptor (CAR)-T cells and chemotherapeutics, have been developed...