You-Wei Zhang
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Explore the profile of You-Wei Zhang including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
732
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Recent Articles
11.
Brognard J, Zhang Y, Puto L, Hunter T
Cancer Res
. 2011 Apr;
71(8):3152-61.
PMID: 21487036
Cancer kinome sequencing studies have identified several protein kinases predicted to possess driver (i.e., causal) mutations. Using bioinformatic applications, we have pinpointed DAPK3 (ZIPK) as a novel cancer-associated kinase with...
12.
Xu L, Li X, Zhang Y, Shu B, Shi Q, Wang Y, et al.
Zhong Xi Yi Jie He Xue Bao
. 2010 Dec;
8(12):1174-9.
PMID: 21144461
Objective: To observe the effects of Yiqi Huayu Recipe, a Chinese compound herbal medicine, on apoptosis of dorsal root ganglion (DRG) neurons and expression of caspase-3 in rats after lumbar...
13.
You Z, Shi L, Zhu Q, Wu P, Zhang Y, Basilio A, et al.
Mol Cell
. 2010 Jan;
36(6):954-69.
PMID: 20064462
In response to DNA double-strand breaks (DSBs), cells sense the DNA lesions and then activate the protein kinase ATM. Subsequent DSB resection produces RPA-coated ssDNA that is essential for activation...
14.
Wang R, Zhang Y, Chen L
Lung Cancer
. 2009 Nov;
69(2):239-44.
PMID: 19913326
FBLN-3 has been identified as an antagonist of angiogenesis which modulates cell morphology, growth, adhesion, and motility. In the present study, we investigated the promoter methylation status of FBLN-3 gene...
15.
Zhang Y, Brognard J, Coughlin C, You Z, Dolled-Filhart M, Aslanian A, et al.
Mol Cell
. 2009 Sep;
35(4):442-53.
PMID: 19716789
ATR and Chk1 are two key protein kinases in the replication checkpoint. Activation of ATR-Chk1 has been extensively investigated, but checkpoint termination and replication fork restart are less well understood....
16.
Shen X, Zhang Y, Deng H, Chen L, Chen P
Zhejiang Da Xue Xue Bao Yi Xue Ban
. 2009 Apr;
38(2):151-7.
PMID: 19363822
Objective: To investigate the impact of intracellular interaction between fibroblasts and colorectal cancer cells on the expression of insulin growth factor binding protein7 (IGFBP7). Methods: Colorectal cancer cells SW480 were...
17.
Geng J, Zhang Y, Huang G, Chen L
World J Gastroenterol
. 2008 Nov;
14(43):6733-7.
PMID: 19034980
Aim: To evaluate the association between X-ray cross-complementing gene 1 (XRCC1) genetic polymorphism Arg399Gln and gastric cancer risk by means of meta-analysis. Methods: We searched PubMed and NCBI up to...
18.
Zhang Y, Deng H, Chen P, Chen L
Zhonghua Bing Li Xue Za Zhi
. 2008 Mar;
36(11):764-7.
PMID: 18307883
Objective: To investigate the expression of extracellular matrix metalloproteinase inducer gene (EMMPRIN) regulated by the interactions between fibroblasts and colon cancer cells, and to study its role in the invasion...
19.
Zhang Y, Hunter T, Abraham R
Cell Cycle
. 2005 Dec;
5(2):125-8.
PMID: 16357541
The replication checkpoint monitors the progress of DNA replication forks during S phase, and delays the firing of later replication origins when active replication forks are stalled due to collisions...
20.
Zhang Y, Otterness D, Chiang G, Xie W, Liu Y, Mercurio F, et al.
Mol Cell
. 2005 Sep;
19(5):607-18.
PMID: 16137618
The Chk1 kinase is a major effector of S phase checkpoint signaling during the cellular response to genotoxic stress. Here, we report that replicative stress induces the polyubiquitination and degradation...