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You-Hsin Lin

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Articles 5
Citations 35
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Recent Articles
1.
Funahashi Y, Ahammad R, Zhang X, Hossen E, Kawatani M, Nakamuta S, et al.
Sci Signal . 2024 Sep; 17(853):eado9852. PMID: 39255336
Structural plasticity of dendritic spines in the nucleus accumbens (NAc) is crucial for learning from aversive experiences. Activation of NMDA receptors (NMDARs) stimulates Ca-dependent signaling that leads to changes in...
2.
Yamahashi Y, Lin Y, Mouri A, Iwanaga S, Kawashima K, Tokumoto Y, et al.
Mol Psychiatry . 2022 Jun; 27(8):3479-3492. PMID: 35665767
Acetylcholine is a neuromodulator critical for learning and memory. The cholinesterase inhibitor donepezil increases brain acetylcholine levels and improves Alzheimer's disease (AD)-associated learning disabilities. Acetylcholine activates striatal/nucleus accumbens dopamine receptor...
3.
Faruk M, Tsuboi D, Yamahashi Y, Funahashi Y, Lin Y, Ahammad R, et al.
J Neurochem . 2021 Dec; 160(3):325-341. PMID: 34878647
The nucleus accumbens (NAc) plays critical roles in emotional behaviors, including aversive learning. Aversive stimuli such as an electric foot shock increase acetylcholine (ACh) in the NAc, and muscarinic signaling...
4.
Lin Y, Yamahashi Y, Kuroda K, Faruk M, Zhang X, Yamada K, et al.
Neurochem Int . 2020 Dec; 143:104935. PMID: 33301817
The nucleus accumbens (NAc) plays a crucial role in various mental activities, including positive and negative reinforcement. We previously hypothesized that a balance between dopamine (DA) and adenosine signals regulates...
5.
Chen Y, Chang K, Hu H, Chen Y, Lin Y, Hsu C, et al.
Nucleic Acids Res . 2017 Mar; 45(10):6011-6022. PMID: 28334864
Frameshifting is an essential process that regulates protein synthesis in many viruses. The ribosome may slip backward when encountering a frameshift motif on the messenger RNA, which usually contains a...