Yong J Lee
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Explore the profile of Yong J Lee including associated specialties, affiliations and a list of published articles.
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120
Citations
6030
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Recent Articles
1.
Vafaeinik F, Zhang L, Lee Y
Exp Cell Res
. 2025 Mar;
447(1):114481.
PMID: 40024506
We previously reported that low extracellular pH promotes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through the mitochondria-mediated caspase signal transduction pathway. In this study, we further investigated the mechanism...
2.
Lee Y, Vafaeinik F, Mouakkad L, Kim D, Song X, Zhang L, et al.
J Cell Biochem
. 2025 Jan;
126(1):e30681.
PMID: 39853862
We previously reported that ferroptosis interplays with apoptosis through the integration of two independent pathways: the endoplasmic reticulum (ER) stress signaling pathway and the mitochondria-dependent apoptotic signaling pathway. In this...
3.
Zhou Z, Arroum T, Luo X, Kang R, Lee Y, Tang D, et al.
Cell Death Differ
. 2024 Mar;
31(4):387-404.
PMID: 38521844
The redox-active protein cytochrome c is a highly positively charged hemoglobin that regulates cell fate decisions of life and death. Under normal physiological conditions, cytochrome c is localized in the...
4.
Kim J, Najy A, Li J, Luo X, Kim H, Choudry M, et al.
J Cell Physiol
. 2022 Aug;
237(11):4180-4196.
PMID: 35994698
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces death receptor-mediated extrinsic apoptosis, specifically in cancer cells, and Bid (BH3-interacting domain death agonist) plays an important role in TRAIL-induced apoptosis. Ferroptosis is...
5.
Liu W, Chen H, Zhu Z, Liu Z, Ma C, Lee Y, et al.
Biomedicines
. 2022 Jun;
10(6).
PMID: 35740445
Ferroptosis is a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides. In this study, we explore the combination of a ferroptosis activator...
6.
Kalimuthu K, Keerthana C, Mohan M, Arivalagan J, Selvan Christyraj J, Firer M, et al.
J Cell Biochem
. 2021 Dec;
123(3):532-542.
PMID: 34935169
Selenium (Se) is incorporated into the body via the selenocysteine (Sec) biosynthesis pathway, which is critical in the synthesis of selenoproteins, such as glutathione peroxidases and thioredoxin reductases. Selenoproteins, which...
7.
Xi Y, Li Y, Xu P, Li S, Liu Z, Tung H, et al.
Sci Adv
. 2021 Sep;
7(36):eabg9241.
PMID: 34516906
Activation of the hepatic stellate cells (HSCs) is a key pathogenic event in liver fibrosis. Protein -glutathionylation (PSSG) of cysteine residues is a distinct form of oxidative response that modifies...
8.
Kalimuthu K, Kim J, Park Y, Luo X, Zhang L, Ku J, et al.
J Cell Physiol
. 2021 Feb;
236(9):6666-6677.
PMID: 33586156
Abnormalities of the tumor vasculature result in insufficient blood supply and development of a tumor microenvironment that is characterized by low glucose concentrations, low extracellular pH, and low oxygen tensions....
9.
Dilly A, Honick B, Frederick R, Elapavaluru A, Velankar S, Makala H, et al.
Transl Res
. 2020 Nov;
229:100-114.
PMID: 33164812
Abundant intraperitoneal (IP) accumulation of extracellular mucus in patients with appendiceal mucinous carcinoma peritonei (MCP) causes compressive organ dysfunction and prevents delivery of chemotherapeutic drugs to cancer cells. We hypothesized...
10.