Yong-Dong Wang
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Explore the profile of Yong-Dong Wang including associated specialties, affiliations and a list of published articles.
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108
Citations
4467
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Recent Articles
1.
Ansari S, Dillard M, Ghonim M, Zhang Y, Stewart D, Canac R, et al.
bioRxiv
. 2025 Feb;
PMID: 39975106
Sonic Hedgehog (SHH) signaling functions in temporal- and context-dependent manners to pattern diverse tissues during embryogenesis. The signal transducer Smoothened (SMO) is activated by sterols, oxysterols, and arachidonic acid (AA)...
2.
Li-Harms X, Lu J, Fukuda Y, Lynch J, Sheth A, Pareek G, et al.
Sci Adv
. 2025 Jan;
11(1):eads8489.
PMID: 39742470
The role of somatic mitochondrial DNA (mtDNA) mutations in leukemogenesis remains poorly characterized. To determine the impact of somatic mtDNA mutations on this process, we assessed the leukemogenic potential of...
3.
Curley M, Rai M, Chuang C, Pagala V, Stephan A, Coleman Z, et al.
Cell Rep Methods
. 2024 Oct;
4(10):100875.
PMID: 39383859
Loss of proteostasis is a hallmark of aging that underlies many age-related diseases. Different cell compartments experience distinctive challenges in maintaining protein quality control, but how aging regulates subcellular proteostasis...
4.
Valentin-Vega Y, Wang Y, Parker M, Patmore D, Kanagaraj A, Moore J, et al.
Sci Rep
. 2024 Jun;
14(1):13009.
PMID: 38844815
No abstract available.
5.
Korff A, Yang X, ODonovan K, Gonzalez A, Teubner B, Nakamura H, et al.
J Clin Invest
. 2024 Apr;
134(8).
PMID: 38618962
No abstract available.
6.
Wright T, Turnis M, Grace C, Li X, Brakefield L, Wang Y, et al.
Mol Cell
. 2024 Mar;
84(7):1338-1353.e8.
PMID: 38503284
MCL-1 is essential for promoting the survival of many normal cell lineages and confers survival and chemoresistance in cancer. Beyond apoptosis regulation, MCL-1 has been linked to modulating mitochondrial metabolism,...
7.
Chen H, Wang Y, Blan A, Almanza-Fuerte E, Bonkowski E, Bajpai R, et al.
bioRxiv
. 2024 Feb;
PMID: 38328212
encodes for the E1 enzyme of the UFMylation cascade, which plays an essential role in ER homeostasis. The clinical phenotypes of UBA5-associated encephalopathy include developmental delays, epilepsy and intellectual disability....
8.
Hall E, Dillard M, Cleverdon E, Zhang Y, Daly C, Ansari S, et al.
Cell
. 2024 Jan;
187(2):276-293.e23.
PMID: 38171360
During development, morphogens pattern tissues by instructing cell fate across long distances. Directly visualizing morphogen transport in situ has been inaccessible, so the molecular mechanisms ensuring successful morphogen delivery remain...
9.
Hunt L, Pagala V, Stephan A, Xie B, Kodali K, Kavdia K, et al.
Nat Commun
. 2023 Nov;
14(1):7348.
PMID: 37963875
Ubiquitination is a post-translational modification initiated by the E1 enzyme UBA1, which transfers ubiquitin to ~35 E2 ubiquitin-conjugating enzymes. While UBA1 loss is cell lethal, it remains unknown how partial...
10.
Korff A, Yang X, ODonovan K, Gonzalez A, Teubner B, Nakamura H, et al.
J Clin Invest
. 2023 Jul;
133(14).
PMID: 37463454
Mutations in HNRNPH2 cause an X-linked neurodevelopmental disorder with features that include developmental delay, motor function deficits, and seizures. More than 90% of patients with hnRNPH2 have a missense mutation...