» Authors » David Finkelstein

David Finkelstein

Explore the profile of David Finkelstein including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 136
Citations 9094
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Ganuza M, Morales-Hernandez A, Van Huizen A, Chabot A, Hall T, Caprio C, et al.
Blood Adv . 2024 Jun; 8(15):4129-4143. PMID: 38905595
Hematopoietic stem cells (HSCs) can generate all blood cells. This ability is exploited in HSC transplantation (HSCT) to treat hematologic disease. A clear understanding of the molecular mechanisms that regulate...
2.
Valentin-Vega Y, Wang Y, Parker M, Patmore D, Kanagaraj A, Moore J, et al.
Sci Rep . 2024 Jun; 14(1):13009. PMID: 38844815
No abstract available.
3.
Jablonowski C, Quarni W, Singh S, Tan H, Hewa Bostanthirige D, Jin H, et al.
Elife . 2024 Mar; 12. PMID: 38488852
Dysregulated pre-mRNA splicing and metabolism are two hallmarks of MYC-driven cancers. Pharmacological inhibition of both processes has been extensively investigated as potential therapeutic avenues in preclinical and clinical studies. However,...
4.
Beauchamp L, Dore V, Villemagne V, Xu S, Finkelstein D, Barnham K, et al.
Neurology . 2023 Oct; 101(22):e2314-e2324. PMID: 37816639
Background And Objectives: There are limited validated biomarkers in Parkinson disease (PD) which substantially hinders the ability to monitor disease progression and consequently measure the efficacy of disease-modifying treatments. Imaging...
5.
Park C, Yoshihara H, Gao Q, Qu C, Iacobucci I, Ghate P, et al.
Cell Rep . 2023 Jul; 42(7):112804. PMID: 37453060
The bone marrow microenvironment (BME) drives drug resistance in acute lymphoblastic leukemia (ALL) through leukemic cell interactions with bone marrow (BM) niches, but the underlying mechanisms remain unclear. Here, we...
6.
Jablonowski C, Quarni W, Singh S, Tan H, Hewa Bostanthirige D, Jin H, et al.
bioRxiv . 2023 Jul; PMID: 37425900
Dysregulated pre-mRNA splicing and metabolism are two hallmarks of MYC-driven cancers. Pharmacological inhibition of both processes has been extensively investigated as potential therapeutic avenues in preclinical and clinical studies. However,...
7.
Jiao J, Curley M, Graca F, Robles-Murguia M, Shirinifard A, Finkelstein D, et al.
Cell Rep . 2023 Jan; 42(1):111970. PMID: 36640359
Protein quality control is important for healthy aging and is dysregulated in age-related diseases. The autophagy-lysosome and ubiquitin-proteasome are key for proteostasis, but it remains largely unknown whether other proteolytic...
8.
Wang R, Bhatt A, Minden-Birkenmaier B, Travis O, Tiwari S, Jia H, et al.
Sci Adv . 2023 Jan; 9(1):eabq3951. PMID: 36608120
Metastases arise from rare cancer cells that successfully adapt to the diverse microenvironments encountered during dissemination through the bloodstream and colonization of distant tissues. How cancer cells acquire the ability...
9.
Ganuza M, Hall T, Myers J, Nevitt C, Sanchez-Lanzas R, Chabot A, et al.
Nat Cell Biol . 2022 Oct; 24(10):1475-1486. PMID: 36202972
Current dogma asserts that the foetal liver (FL) is an expansion niche for recently specified haematopoietic stem cells (HSCs) during ontogeny. Indeed, between embryonic day of development (E)12.5 and E14.5,...
10.
Youn Y, Hou S, Wu C, Kawauchi D, Orr B, Robinson G, et al.
Genes Dev . 2022 Jul; 36(11-12):737-751. PMID: 35798383
The primary cilium, a signaling organelle projecting from the surface of a cell, controls cellular physiology and behavior. The presence or absence of primary cilia is a distinctive feature of...