Yonatan Y Mahller
Overview
Explore the profile of Yonatan Y Mahller including associated specialties, affiliations and a list of published articles.
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13
Citations
484
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Recent Articles
1.
Ogunyemi D, Mahller Y, Wohlmuth C, Eppey R, Tangchitnob E, Alexander C
J Reprod Med
. 2011 Oct;
56(9-10):398-404.
PMID: 22010523
Objective: To determine if the DISC (Dominance, Influence, Steadiness/Submission, and Conscientious/ Compliance) assessment correlates with obstetrics and gynecology resident performance. Study Design: A total of 46 residents completed the DISC...
2.
Kaimal V, Chu Z, Mahller Y, Papahadjopoulos-Sternberg B, Cripe T, Holland S, et al.
Mol Imaging Biol
. 2010 Sep;
13(5):886-97.
PMID: 20838909
Purpose: Nanovesicles composed of the phospholipid dioleylphosphatidylserine (DOPS) and a fusogenic protein, saposin C (SapC), selectively target and induce apoptotic cell death in a variety of human cancer cells in...
3.
Maldonado A, Klanke C, Jegga A, Aronow B, Mahller Y, Cripe T, et al.
J Gene Med
. 2010 Jul;
12(7):613-23.
PMID: 20603890
Background: Expression profile analyses of midkine (MDK), a multifunctional protein important in development but repressed postnataly, indicate that it is highly expressed in approximately 80% of adult carcinomas and many...
4.
Qi X, Chu Z, Mahller Y, Stringer K, Witte D, Cripe T
Clin Cancer Res
. 2009 Sep;
15(18):5840-51.
PMID: 19737950
Purpose: Saposin C is a multifunctional protein known to activate lysosomal enzymes and induce membrane fusion in an acidic environment. Excessive accumulation of lipid-coupled saposin C in lysosomes is cytotoxic....
5.
Cripe T, Wang P, Marcato P, Mahller Y, Lee P
Mol Ther
. 2009 Aug;
17(10):1677-82.
PMID: 19672244
Recent studies in a variety of leukemias and solid tumors indicate that there is significant heterogeneity with respect to tumor-forming ability within a given population of tumor cells, suggesting that...
6.
Mahller Y, Williams J, Baird W, Mitton B, Grossheim J, Saeki Y, et al.
PLoS One
. 2009 Jan;
4(1):e4235.
PMID: 19156211
Background: Although disease remission can frequently be achieved for patients with neuroblastoma, relapse is common. The cancer stem cell theory suggests that rare tumorigenic cells, resistant to conventional therapy, are...
7.
Johansson G, Mahller Y, Collins M, Kim M, Nobukuni T, Perentesis J, et al.
Mol Cancer Ther
. 2008 May;
7(5):1237-45.
PMID: 18483311
Malignant peripheral nerve sheath tumors (MPNST) are chemoresistant sarcomas with poor 5-year survival that arise in patients with neurofibromatosis type 1 (NF1) or sporadically. We tested three drugs for single...
8.
Currier M, Gillespie R, Sawtell N, Mahller Y, Stroup G, Collins M, et al.
Mol Ther
. 2008 Apr;
16(5):879-85.
PMID: 18388918
Oncolytic herpes simplex virus (oHSV) mutants are under development as anticancer therapeutics. One such vector, rRp450, is ICP6-deleted and expresses a prodrug enzyme for cyclophosphamide (CPA) (rat CYP2B1). Little is...
9.
Mahller Y, Vaikunth S, Ripberger M, Baird W, Saeki Y, Cancelas J, et al.
Cancer Res
. 2008 Feb;
68(4):1170-9.
PMID: 18281493
Malignant solid tumors remain a significant clinical challenge, necessitating innovative therapeutic approaches. Oncolytic viral therapy is a nonmutagenic, biological anticancer therapeutic shown to be effective against human cancer in early...
10.
Mahller Y, Vaikunth S, Currier M, Miller S, Ripberger M, Hsu Y, et al.
Mol Ther
. 2007 Jan;
15(2):279-86.
PMID: 17235305
Malignant peripheral nerve sheath tumors (MPNSTs), driven in part by hyperactive Ras and epidermal growth factor receptor (EGFR) signaling, are often incurable. Testing of therapeutics for MPNST has been hampered...