Yolanda Alvarez
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Explore the profile of Yolanda Alvarez including associated specialties, affiliations and a list of published articles.
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63
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1046
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Recent Articles
1.
OBrien J, Colucci P, Alvarez Y, Kennedy B
Adv Exp Med Biol
. 2025 Feb;
1468:491-495.
PMID: 39930243
Photoreceptor and retinal pigment epithelium (RPE) dysfunction in inherited retinal degenerations (IRDs) and age-related macular degeneration (AMD) necessitate innovative therapies to preserve vision. Vision impairment incurs a substantial global economic...
2.
Vlasakakis G, Alvarez Y, Hart T, Ho Y, Ellis C
Clin Pharmacol Drug Dev
. 2025 Jan;
PMID: 39844679
A randomized, partially blinded, placebo-controlled, crossover study in 48 healthy adults assessed the effect of momelotinib on the heart rate-corrected QT interval (QTc) using the Fridericia formula (QTcF). QTc was...
3.
Nijjar J, Abbott-Banner K, Alvarez Y, Aston N, Bass D, Bentley J, et al.
Ann Rheum Dis
. 2024 Oct;
PMID: 39419538
Objectives: The objective of this study was to evaluate efficacy, safety and tolerability of the first-in-class, anti-CCL17 monoclonal antibody, GSK3858279, in treating knee osteoarthritis (OA) pain. Methods: This was a...
4.
McCann T, Sundaramurthi H, Walsh C, Virdi S, Alvarez Y, Sapetto-Rebow B, et al.
FASEB J
. 2024 Oct;
38(19):e70086.
PMID: 39360639
Inherited retinal diseases (IRDs) are a rare group of eye disorders characterized by progressive dysfunction and degeneration of retinal cells. In this study, we characterized the raifteirí (raf) zebrafish, a...
5.
Boyle Y, Hijma H, Rees J, Nijjar J, Panoilia E, Alvarez Y, et al.
Clin Transl Sci
. 2024 Sep;
17(9):e13873.
PMID: 39250326
C-C Motif Chemokine Ligand 17 (CCL17) is a chemokine that binds and signals through the G-protein coupled CC-chemokine receptor 4 and has been implicated in the development of inflammatory and...
6.
Alvarez Y, Mancebo C, Alonso S, Montero O, Fernandez N, Sanchez Crespo M
Redox Biol
. 2024 May;
73:103187.
PMID: 38744190
Monocyte-derived dendritic cells (MDDCs) are key players in the defense against fungal infection because of their outstanding capacity for non-opsonic phagocytosis and phenotypic plasticity. Accordingly, MDDCs rewire metabolism to meet...
7.
Fernandez J, Marin A, Rosales R, Penrice-Randal R, Mlcochova P, Alvarez Y, et al.
Biochim Biophys Acta Mol Basis Dis
. 2024 Apr;
1870(5):167193.
PMID: 38648902
SARS-CoV-2 infection can cause severe pneumonia, wherein exacerbated inflammation plays a major role. This is reminiscent of the process commonly termed cytokine storm, a condition dependent on a disproportionated production...
8.
Sanchez A, Colucci P, Moran A, Moya Lopez A, Colligris B, Alvarez Y, et al.
Open Res Eur
. 2024 Jan;
3:48.
PMID: 38283058
Introduction: Cigarette smoking adversely affects multiple aspects of human health including eye disorders such as age-related macular degeneration, cataracts and dry eye disease. However, there remains a knowledge gap in...
9.
Fernandez J, Mancebo C, Garcinuno S, March G, Alvarez Y, Alonso S, et al.
Genes Immun
. 2023 Dec;
25(1):43-54.
PMID: 38146001
The utilization of host-cell machinery during SARS-CoV-2 infection can overwhelm the protein-folding capacity of the endoplasmic reticulum and activate the unfolded protein response (UPR). The IRE1α-XBP1 arm of the UPR...
10.
Sanchez A, Alvarez Y, Colligris B, Kennedy B
Open Res Eur
. 2023 Aug;
1:92.
PMID: 37645173
The optokinetic response (OKR) is an effective behavioural assay to investigate functional vision in zebrafish. The rapid and widespread use of gene editing, drug screening and environmental modulation technologies has...