» Authors » Yogita Kanan

Yogita Kanan

Explore the profile of Yogita Kanan including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 26
Citations 356
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Kanan Y, Zhang J, Bernardo-Colon A, Debnath S, Khan M, Becerra S, et al.
Free Radic Biol Med . 2025 Feb; 231:48-56. PMID: 39984061
Retinitis pigmentosa (RP) is a disorder that results in the death of rod photoreceptors in the retina, caused by several different mutations. As rods are 95 % of the photoreceptors...
2.
Kanan Y, Hackett S, Hsueh H, Khan M, Ensign L, Campochiaro P
Free Radic Biol Med . 2023 Feb; 198:118-122. PMID: 36736930
Retinitis pigmentosa (RP) is caused by many different mutations that promote the degeneration of rod photoreceptors and have no direct effect on cones. After the majority of rods have died...
3.
Kanan Y, Hackett S, Taneja K, Khan M, Campochiaro P
Free Radic Biol Med . 2022 Feb; 181:143-153. PMID: 35134532
Retinitis pigmentosa occurs due to mutations that cause rod photoreceptor degeneration. Once most rods are lost, gradual degeneration of cone photoreceptors occurs. Oxidative damage and abnormal glucose metabolism have been...
4.
Tsujinaka H, Fu J, Shen J, Yu Y, Hafiz Z, Kays J, et al.
Nat Commun . 2020 Feb; 11(1):694. PMID: 32019921
Neovascular age-related macular degeneration and diabetic retinopathy are prevalent causes of vision loss requiring frequent intravitreous injections of VEGF-neutralizing proteins, and under-treatment is common and problematic. Here we report incorporation...
5.
Ikeuchi T, Kanan Y, Long D, de Vega S, Hozumi K, Nomizu M, et al.
Microvasc Res . 2020 Feb; 129:103986. PMID: 32017943
Wet age-related macular degeneration (AMD) and diabetic retinopathy are the leading causes of blindness through increased angiogenesis. Although VEGF-neutralizing proteins provide benefit, inconsistent responses indicate a need for new therapies....
6.
Kanan Y, Khan M, Lorenc V, Long D, Chadha R, Sciamanna J, et al.
J Neurochem . 2018 Oct; 148(2):307-318. PMID: 30315650
Metipranolol is a β-adrenergic receptor antagonist that is given orally for the treatment of hypertension and also applied topically to the cornea for treating glaucoma. It also inhibits nitrosative stress...
7.
Long D, Kanan Y, Shen J, Hackett S, Liu Y, Hafiz Z, et al.
JCI Insight . 2018 May; 3(10). PMID: 29769445
Intraocular injections of VEGF-neutralizing proteins provide tremendous benefits in patients with choroidal neovascularization (NV) due to age-related macular degeneration (AMD), but during treatment some patients develop retinal atrophy. Suggesting that...
8.
Lima E Silva R, Kanan Y, Mirando A, Kim J, Shmueli R, Lorenc V, et al.
Sci Transl Med . 2017 Jan; 9(373). PMID: 28100839
Vascular endothelial growth factor (VEGF)-neutralizing proteins provide benefit in several retinal and choroidal vascular diseases, but some patients still experience suboptimal outcomes, and the need for frequent intraocular injections is...
9.
Kanan Y, Al-Ubaidi M
Adv Exp Med Biol . 2015 Oct; 854:649-54. PMID: 26427471
Lack of tyrosine O Sulfation compromises both rod and cone electroretinographic responses emphasizing the importance of this post-translational modification for vision. To identify tyrosine sulfated proteins in retina, cow retinal...
10.
Rajala R, Kanan Y, Anderson R
Adv Exp Med Biol . 2015 Oct; 854:419-24. PMID: 26427440
Serine/threonine kinase Akt is a downstream effector of insulin receptor/PI3K pathway that is involved in many processes, including providing neuroprotection to stressed rod photoreceptor cells. Akt signaling is known to...