Yini Li
Overview
Explore the profile of Yini Li including associated specialties, affiliations and a list of published articles.
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59
Citations
471
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Recent Articles
21.
Yu S, Tu R, Chen Z, Song J, Li P, Hu F, et al.
BMC Med Genomics
. 2023 Sep;
16(1):209.
PMID: 37670284
Background: Gastric cancer (GC) is one of the most common malignancies, affected by several genetic loci in the clinical phenotype. This study aimed to determine the association between PTGER4 and...
22.
Dou X, Xiao Y, Shen C, Wang K, Wu T, Liu C, et al.
Nat Cell Biol
. 2023 Aug;
25(9):1359-1368.
PMID: 37640841
N-methyladenosine (mA) methylation can be deposited on chromatin-associated RNAs (caRNAs) by the RNA methyltransferase complex (MTC) to regulate chromatin state and transcription. However, the mechanism by which MTC is recruited...
23.
Li Y, Tian L, Zhang Y, Shi Y
Life Sci Alliance
. 2023 Jul;
6(9).
PMID: 37402593
In , onset of programmed cell death is marked with the activation of CED-3, a process that requires assembly of the CED-4 apoptosome. Activated CED-3 forms a holoenzyme with the...
24.
Li Y, Chen L, Feng L, Li M
Ultrasound Med Biol
. 2023 Jun;
49(9):1930-1939.
PMID: 37391293
Objective: The aim of the work described here was to provide an evidence-based evaluation of contrast-enhanced ultrasonography (CEUS) in acute kidney injury (AKI) and assess variations in renal microperfusion with...
25.
Li Y, Dou X, Liu J, Xiao Y, Zhang Z, Hayes L, et al.
Nat Neurosci
. 2023 Jun;
26(8):1328-1338.
PMID: 37365312
Repeat expansion in C9ORF72 is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Here we show that N-methyladenosine (mA), the most prevalent internal mRNA...
26.
Zhao K, Li Y, Guo M, Ma L, Dang B
J Biol Chem
. 2023 May;
299(6):104831.
PMID: 37201587
Viral proteases play key roles in viral replication, and they also facilitate immune escape by proteolyzing diverse target proteins. Deep profiling of viral protease substrates in host cells is beneficial...
27.
Zhang H, Yan J, Lu Z, Zhou Y, Zhang Q, Cui T, et al.
Cell Discov
. 2023 May;
9(1):48.
PMID: 37193681
Life science studies involving clustered regularly interspaced short palindromic repeat (CRISPR) editing generally apply the best-performing guide RNA (gRNA) for a gene of interest. Computational models are combined with massive...
28.
Dou X, Huang L, Xiao Y, Liu C, Li Y, Zhang X, et al.
Protein Cell
. 2023 Apr;
14(9):683-697.
PMID: 37030005
METTL3 and METTL14 are two components that form the core heterodimer of the main RNA m6A methyltransferase complex (MTC) that installs m6A. Surprisingly, depletion of METTL3 or METTL14 displayed distinct...
29.
Yu Z, Lu Z, Li J, Wang Y, Wu P, Li Y, et al.
Nat Commun
. 2022 Dec;
13(1):7545.
PMID: 36509752
CRISPR technology holds significant promise for biological studies and gene therapies because of its high flexibility and efficiency when applied in mammalian cells. But endonuclease (e.g., Cas9) potentially generates undesired...
30.
Ling J, Bygrave A, Santiago C, Carmen-Orozco R, Trinh V, Yu M, et al.
Nat Commun
. 2022 Oct;
13(1):5773.
PMID: 36182931
Precise and reliable cell-specific gene delivery remains technically challenging. Here we report a splicing-based approach for controlling gene expression whereby separate translational reading frames are coupled to the inclusion or...