Yijen Wu
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Explore the profile of Yijen Wu including associated specialties, affiliations and a list of published articles.
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25
Citations
405
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Recent Articles
1.
Reynolds W, Votava-Smith J, Gabriel G, Lee V, Rajagopalan V, Wu Y, et al.
J Clin Med
. 2024 Oct;
13(19).
PMID: 39407833
Brain magnetic resonance imaging (MRI) of infants with congenital heart disease (CHD) shows brain immaturity assessed via a cortical-based semi-quantitative score. Our primary aim was to develop an infant paralimbic-related...
2.
Constantinesco N, Srikanth S, De Vito L, Moras C, Ramasubramanian V, Chinnappan B, et al.
Sci Rep
. 2024 May;
14(1):11124.
PMID: 38750107
Influenza is a significant public health and economic threat around the world. Epidemiological studies have demonstrated a close association between influenza pandemics and cardiovascular mortality. Moreover, it has been shown...
3.
Akinyele O, Munir A, Johnson M, Perez M, Gao Y, Foley J, et al.
Dis Model Mech
. 2024 Mar;
17(6).
PMID: 38463005
Snyder-Robinson syndrome (SRS) is a rare X-linked recessive disorder caused by a mutation in the SMS gene, which encodes spermine synthase, and aberrant polyamine metabolism. SRS is characterized by intellectual...
4.
Wang H, Lu J, Stevens T, Roberts A, Mandel J, Avula R, et al.
Cell Rep
. 2023 Jul;
42(8):112830.
PMID: 37481724
MYC proto-oncogene dysregulation alters metabolism, translation, and other functions in ways that support tumor induction and maintenance. Although Myc mice are healthier and longer-lived than control mice, the long-term ramifications...
5.
Shang P, Simpson J, Taylor G, Sutherland D, Welsh O, Aravamudhan P, et al.
Nat Commun
. 2023 May;
14(1):2615.
PMID: 37147336
Mammalian orthoreovirus (reovirus) infects most mammals and is associated with celiac disease in humans. In mice, reovirus infects the intestine and disseminates systemically to cause serotype-specific patterns of disease in...
6.
Yagi H, Cui C, Saydmohammed M, Gabriel G, Baker C, Devine W, et al.
bioRxiv
. 2023 May;
PMID: 37131609
Left-right patterning disturbance can cause severe birth defects, but it remains least understood of the three body axes. We uncovered an unexpected role for metabolic regulation in left-right patterning. Analysis...
7.
Akinyele O, Munir A, Johnson M, Perez M, Gao Y, Foley J, et al.
bioRxiv
. 2023 Jan;
PMID: 36711956
Polyamines (putrescine, spermidine, and spermine) are essential molecules for normal cellular functions and are subject to strict metabolic regulation. Mutations in the gene encoding spermine synthase (SMS) lead to accumulation...
8.
Zusman B, Wu Y, Kochanek P, Vagni V, Janesko-Feldman K, Gerzanich V, et al.
Crit Care Med
. 2023 Jan;
51(2):e45-e59.
PMID: 36661464
Objectives: Addressing traumatic brain injury (TBI) heterogeneity is increasingly recognized as essential for therapy translation given the long history of failed clinical trials. We evaluated differential effects of a promising...
9.
Bharathi S, Zhang B, Paul E, Zhang Y, Schmidt A, Fowler B, et al.
Mol Genet Metab
. 2022 Nov;
137(4):342-348.
PMID: 36335793
GM3 synthase (GM3S) deficiency is a rare neurodevelopmental disorder caused by an inability to synthesize gangliosides, for which there is currently no treatment. Gangliosides are brain-enriched, plasma membrane glycosphingolipids with...
10.
Teekakirikul P, Zhu W, Gabriel G, Young C, Williams K, Martin L, et al.
HGG Adv
. 2021 Dec;
2(3).
PMID: 34888534
Bicuspid aortic valve (BAV) with ~1%-2% prevalence is the most common congenital heart defect (CHD). It frequently results in valve disease and aorta dilation and is a major cause of...