Yifan Tai
Overview
Explore the profile of Yifan Tai including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
121
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Recent Articles
1.
Tai Y, Chow A, Han S, Coker C, Ma W, Gu Y, et al.
EMBO Mol Med
. 2024 Jul;
16(8):1957-1980.
PMID: 38956205
Acquired resistance to PARP inhibitors (PARPi) remains a treatment challenge for BRCA1/2-mutant breast cancer that drastically shortens patient survival. Although several resistance mechanisms have been identified, none have been successfully...
2.
Liu Z, Zhang X, Wang Y, Tai Y, Yao X, Midgley A
Biomolecules
. 2024 Apr;
14(4).
PMID: 38672525
There was an error in the original publication [...].
3.
Liu Z, Zhang X, Wang Y, Tai Y, Yao X, Midgley A
Biomolecules
. 2023 Aug;
13(8).
PMID: 37627244
Myofibroblasts are the principal effector cells driving fibrosis, and their accumulation in tissues is a fundamental feature of fibrosis. Essential pathways have been identified as being central to promoting myofibroblast...
4.
Wang Y, Pan T, Wei X, Su F, Li A, Tai Y, et al.
Commun Chem
. 2023 Jan;
5(1):81.
PMID: 36697908
Enzymatic compartments, inspired by cell compartmentalization, which bring enzymes and substrates together in confined environments, are of particular interest in ensuring the enhanced catalytic efficiency and increased lifetime of encapsulated...
5.
Biswas A, Han S, Tai Y, Ma W, Coker C, Quinn S, et al.
Cancer Discov
. 2022 Jan;
12(4):1002-1021.
PMID: 35078784
Significance: Treatment with the EGFR TKI osimertinib prolongs the survival of patients with EGFR-mutant lung cancer; however, patients develop metastatic relapses, often to the brain. We identified a novel intracellular...
6.
Tai Y, Woods E, Dally J, Kong D, Steadman R, Moseley R, et al.
Biomolecules
. 2021 Aug;
11(8).
PMID: 34439762
Myofibroblasts are contractile, α-smooth muscle actin-positive cells with multiple roles in pathophysiological processes. Myofibroblasts mediate wound contractions, but their persistent presence in tissues is central to driving fibrosis, making them...
7.
Zhang L, Yan H, Tai Y, Xue Y, Wei Y, Wang K, et al.
Int J Mol Sci
. 2021 Feb;
22(4).
PMID: 33557232
Fibrosis is characterized by excessive production of disorganized collagen- and fibronectin-rich extracellular matrices (ECMs) and is driven by the persistence of myofibroblasts within tissues. A key protein contributing to myofibroblast...