Adam C Midgley
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Explore the profile of Adam C Midgley including associated specialties, affiliations and a list of published articles.
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65
Citations
1125
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Recent Articles
1.
Li D, Yi G, Cao G, Midgley A, Yang Y, Yang D, et al.
Small
. 2025 Mar;
:e2410124.
PMID: 40079102
The utilization of plant-derived exosome-like nanovesicles (ELNs) as nanocarriers for oral delivery of bioactives has garnered significant attention. However, their distinctive lipid membrane composition may result in elevated membrane permeability...
2.
Zhang J, Zhao M, Xi Z, Liu X, Feng L, Bai J, et al.
J Am Chem Soc
. 2025 Mar;
PMID: 40063899
Gene-targeted therapies are revolutionizing cancer treatment due to their high specificity and low toxicity. Among these, ribozymes hold promise as independent gene therapy agents capable of directly cleaving target mRNAs....
3.
Wang L, Li Y, He Y, Fang Y, Mimuro H, Midgley A, et al.
Cell Struct Funct
. 2025 Mar;
PMID: 40058796
Macropinocytosis, a type of large-scale endocytosis process, is induced in macrophages by extracellular stimuli, including lipopolysaccharide (LPS). In addition to uptake function, emerging evidence supports a link between macropinocytosis and...
4.
Sun X, Li Y, He Y, Cheng L, Wang L, Wei J, et al.
Cell Commun Signal
. 2025 Feb;
23(1):75.
PMID: 39934854
Background: Circular dorsal ruffles (CDRs) are large and rounded membrane ruffles that function as precursors of macropinocytosis. We recently reported that CDRs form in Hep3B hepatocellular carcinoma (HCC) cells, but...
5.
Liu Q, Gao Z, Zhang X, Duan Q, Zhang Y, Midgley A, et al.
Nat Commun
. 2025 Jan;
16(1):1123.
PMID: 39875380
Nanozymes play a pivotal role in mitigating excessive oxidative stress, however, determining their specific enzyme-mimicking activities for intracellular free radical scavenging is challenging due to endo-lysosomal entrapment. In this study,...
6.
Wan J, Jiang J, Yu X, Zhou J, Wang Y, Fu S, et al.
Int J Biol Macromol
. 2025 Jan;
298:140058.
PMID: 39832583
Cartilage defect repair remains a challenge for clinicians due to the limited self-healing capabilities of cartilage. Microenvironment-specific biomimetic hydrogels have shown great potential in cartilage regeneration because of their excellent...
7.
Xing M, Wang F, Chu R, Wang H, Sun Y, Qian M, et al.
Adv Sci (Weinh)
. 2024 Dec;
12(5):e2409744.
PMID: 39656938
Decellularized allografts have emerged as promising candidates for vascular bypass grafting, owing to their inherent bioactivity and minimal immunogenicity. However, graft failure that results from suboptimal regeneration and pathological remodeling...
8.
Liu Y, Chen S, Huang H, Midgley A, Han Z, Han Z, et al.
Adv Healthc Mater
. 2024 Nov;
14(2):e2403068.
PMID: 39520385
Liver fibrosis poses a significant global health burden, in which hepatic stellate cells (HSCs) play a crucial role. Targeted nanomedicine delivery systems directed at HSCs have shown immense potential in...
9.
Jin Z, Midgley A
Biomolecules
. 2024 Oct;
14(10).
PMID: 39456181
Naturally sourced biomolecules and their derivatives have had significant historical impacts in terms of their biomedical application [...].
10.
Zhang P, Zhao X, Zhang S, Li G, Midgley A, Fang Y, et al.
Curr Res Food Sci
. 2024 Oct;
9:100865.
PMID: 39416367
Cultivated meat (CM) provides a potential solution to meet the rising demand for eco-friendly meat supply systems. Recent efforts focus on producing CM that replicates the architecture and textural toughness...