Yichen Xiang
Overview
Explore the profile of Yichen Xiang including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
83
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0
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Recent Articles
1.
Tong M, Palmer N, Dailamy A, Kumar A, Khaliq H, Han S, et al.
Nat Biomed Eng
. 2024 Aug;
9(1):109-126.
PMID: 39187662
Circularization can improve RNA persistence, yet simple and scalable approaches to achieve this are lacking. Here we report two methods that facilitate the pursuit of circular RNAs (cRNAs): cRNAs developed...
2.
Toure M, Motoyama K, Xiang Y, Urgiles J, Kabinger F, Koglin A, et al.
bioRxiv
. 2024 Jul;
PMID: 38952800
Highlights: - KI-CDK9d-32 is a highly potent and selective CDK9 degrader. - KI-CDK9d-32 leads to rapid downregulation of MYC protein and mRNA transcripts levels. - KI-CDK9d-32 represses canonical MYC pathways...
3.
Xiang Y, Katrekar D, Mali P
Methods
. 2022 Jul;
205:158-166.
PMID: 35779766
Adenosine deaminases acting on RNA (ADARs) can be repurposed to achieve site-specific A-to-I RNA editing by recruiting them to a target of interest via an ADAR-recruiting guide RNA (adRNA). In...
4.
Zhu L, Xiang Y, Song A
IEEE Trans Haptics
. 2022 Apr;
15(3):497-507.
PMID: 35389870
Unsorted three dimensional (3D) points are commonly acquired from modern tools and they become popular in many virtual reality applications. In order to produce the haptic feedback to enrich the...
5.
Katrekar D, Yen J, Xiang Y, Saha A, Meluzzi D, Savva Y, et al.
Nat Biotechnol
. 2022 Feb;
40(6):938-945.
PMID: 35145312
Recruiting endogenous adenosine deaminases using exogenous guide RNAs to edit cellular RNAs is a promising therapeutic strategy, but editing efficiency and durability remain low using current guide RNA designs. In...
6.
Katrekar D, Xiang Y, Palmer N, Saha A, Meluzzi D, Mali P
Elife
. 2022 Jan;
11.
PMID: 35044296
Adenosine deaminases acting on RNA (ADARs) can be repurposed to enable programmable RNA editing, however their exogenous delivery leads to transcriptome-wide off-targeting, and additionally, enzymatic activity on certain RNA motifs,...