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Yi T Koh

Explore the profile of Yi T Koh including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 136
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Recent Articles
1.
Byun J, Koh Y, Jang S, Witcher J, Chan J, Pustilnik A, et al.
Sci Rep . 2021 Sep; 11(1):18671. PMID: 34548595
The selective Bruton tyrosine kinase (BTK) inhibitor poseltinib has been shown to inhibit the BCR signal transduction pathway and cytokine production in B cells (Park et al. Arthritis Res. Ther....
2.
Noval Rivas M, Koh Y, Chen A, Nguyen A, Lee Y, Lawson G, et al.
J Clin Invest . 2012 Apr; 122(5):1933-47. PMID: 22466646
Tregs expressing the transcription factor Foxp3 suppress self-reactive T cells, prevent autoimmunity, and help contain immune responses to foreign antigens, thereby limiting the potential for inadvertent tissue damage. Mutations in...
3.
Theofilopoulos A, Gonzalez-Quintial R, Lawson B, Koh Y, Stern M, Kono D, et al.
Nat Rev Rheumatol . 2010 Feb; 6(3):146-56. PMID: 20142813
Evidence strongly suggests that excessive or protracted signaling, or both, by cell-surface or intracellular innate immune receptors is central to the pathogenesis of most autoimmune and autoinflammatory rheumatic diseases. The...
4.
Koh Y, Gray A, Higgins S, Hubby B, Kast W
Prostate . 2009 Jan; 69(6):571-84. PMID: 19143030
Background: Androgen ablation (AA) causes apoptosis of normal and neoplastic prostate cells. It is a standard treatment for advanced prostate cancer. Androgen ablation-mediated immunological effects include bone marrow hyperplasia, thymic...
5.
Koh Y, Higgins S, Weber J, Kast W
J Transl Med . 2006 Oct; 4:42. PMID: 17059610
Incomplete Freund's adjuvant (IFA) serves as a carrier for water-in-oil emulsion (W/O) vaccines. The stability of such emulsions greatly affects vaccine safety and efficacy since continued presence of antigen depots...