Yi-Chien Tsai
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Explore the profile of Yi-Chien Tsai including associated specialties, affiliations and a list of published articles.
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22
Citations
435
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Recent Articles
11.
Laurent A, Siret A, Ignacimouttou C, Panchal K, Diop M, Jenni S, et al.
Clin Cancer Res
. 2020 Mar;
26(13):3307-3318.
PMID: 32220889
Purpose: Children with Down syndrome (constitutive trisomy 21) that develop acute lymphoblastic leukemia (DS-ALL) have a 3-fold increased likelihood of treatment-related mortality coupled with a higher cumulative incidence of relapse,...
12.
Huang Y, Mouttet B, Warnatz H, Risch T, Rietmann F, Frommelt F, et al.
Cancer Cell
. 2019 Nov;
36(6):630-644.e9.
PMID: 31735627
The chimeric transcription factor TCF3-HLF defines an incurable acute lymphoblastic leukemia subtype. Here we decipher the regulome of endogenous TCF3-HLF and dissect its essential transcriptional components and targets by functional...
13.
Prediction of venetoclax activity in precursor B-ALL by functional assessment of apoptosis signaling
Seyfried F, Demir S, Horl R, Stirnweiss F, Ryan J, Scheffold A, et al.
Cell Death Dis
. 2019 Jul;
10(8):571.
PMID: 31358732
Deregulated cell death pathways contribute to leukemogenesis and treatment failure in B-cell precursor acute lymphoblastic leukemia (BCP-ALL). Intrinsic apoptosis signaling is regulated by different proapoptotic and antiapoptotic molecules: proapoptotic BCL-2...
14.
De Smedt R, Peirs S, Morscio J, Matthijssens F, Roels J, Reunes L, et al.
Haematologica
. 2018 Aug;
104(1):e17-e20.
PMID: 30076176
No abstract available.
15.
Lin Y, Lin G, Lee J, Lee M, Tsai C, Hsu Y, et al.
Medicine (Baltimore)
. 2016 Apr;
95(17):e3554.
PMID: 27124064
Migraine has been associated with sleep disturbances. Relationship between sleep quality and migraine frequency is yet to be determined. The present study aimed to investigate sleep disturbances among low-frequency, moderate-frequency,...
16.
Lin I, Chen D, Chang Y, Lee Y, Su C, Cheng C, et al.
PLoS One
. 2015 Feb;
10(2):e0118453.
PMID: 25706888
Oncogenic transformation of normal cells often involves epigenetic alterations, including histone modification and DNA methylation. We conducted whole-genome bisulfite sequencing to determine the DNA methylomes of normal breast, fibroadenoma, invasive...
17.
Globo-H ceramide shed from cancer cells triggers translin-associated factor X-dependent angiogenesis
Cheng J, Wang S, Lin J, Tsai Y, Yu J, Wu J, et al.
Cancer Res
. 2014 Oct;
74(23):6856-66.
PMID: 25281721
Tumor angiogenesis is a critical element of cancer progression, and strategies for its selective blockade are still sought. Here, we examine the angiogenic effects of Globo-H ceramide (GHCer), the most...
18.
Huang J, Tsai Y, Chang Y, Wu J, Hung J, Lin K, et al.
J Immunol
. 2014 Jan;
192(4):1972-81.
PMID: 24465013
Strategies for cancer immunotherapy include activating immune system for therapeutic benefit or blockade of immune checkpoints. To harness innate immunity to fight cancer, α-galactosylceramide (α-GalCer) has been used to activate...
19.
Tsai Y, Chiao C, Yi-Feng Chang I, Chen D, Liu T, Hua K, et al.
Cancers (Basel)
. 2013 Nov;
3(2):1996-2013.
PMID: 24212793
We have previously identified large megabase-sized hypomethylated zones in the genome of the breast cancer cell line MCF-7 using the TspRI-ExoIII technique. In this report, we used a more convenient...
20.
Lai C, Hung J, Lin H, Yu A, Chen S, Tsai Y, et al.
Vaccine
. 2010 Jul;
28(31):4945-54.
PMID: 20653103
We had isolated a high molecular weight polysaccharide fraction, designated as F3, and performed a comprehensive analysis of its immunomodulatory and adjuvant activities in vivo and in vitro. In vivo,...