Alice L Yu
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Explore the profile of Alice L Yu including associated specialties, affiliations and a list of published articles.
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152
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3960
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Recent Articles
1.
Fan T, Yeo H, Hung T, Chang N, Tang Y, Yu J, et al.
J Biol Chem
. 2025 Mar;
:108368.
PMID: 40024474
Metastasis is a major cause of cancer-related morbidity and mortality. The overexpression of the sialyltransferase ST3GAL1 in breast cancer correlates with metastasis. However, the molecular mechanisms underlying the effect of...
2.
Umaretiya P, Naranjo A, Zhang F, Park J, Weiss B, Granger M, et al.
JAMA Netw Open
. 2025 Feb;
8(2):e2458531.
PMID: 39951269
Importance: Whether population-based racial and ethnic survival disparities for children with high-risk neuroblastoma persist in the clinical trial setting is unknown. Objective: To investigate racial and ethnic survival disparities among...
3.
Tsai H, Hsiao F, Yu A, Juang J, Yu J, Chu P
Stem Cell Rev Rep
. 2025 Jan;
PMID: 39841369
Human-induced pluripotent stem cell (hiPSC) technology has been applied in pathogenesis studies, drug screening, tissue engineering, and stem cell therapy, and patient-specific hiPSC-derived cardiomyocytes (hiPSC-CMs) have shown promise in disease...
4.
Hung J, Chiou S, Tang Y, Huang J, Lo F, Yu A
Drug Des Devel Ther
. 2024 Nov;
18:5323-5332.
PMID: 39583633
Purpose: The glycolipid α-galactosylceramide (α-GalCer), when presented by CD1d, can modulate the immune system through the activation of natural killer T (NKT) cells. Previously, we synthesized over 30 analogs of...
5.
Wu T, Hung J, Hung T, Wang Y, Wu J, Yu A
Biomed Pharmacother
. 2024 Jul;
177:117040.
PMID: 38959605
Invariant natural killer T cell (iNKT) cells produce large amounts of cytokines in response to α-Galactosylceramide (α-GalCer) stimulation. An analog containing two phenyl rings on the acyl chain, C34, was...
6.
Giang L, Wu K, Lee W, Chu S, Do A, Changou C, et al.
J Exp Clin Cancer Res
. 2023 Dec;
42(1):346.
PMID: 38124207
Background: Atypical teratoid rhabdoid tumors (ATRT) is a rare but aggressive malignancy in the central nervous system, predominantly occurring in early childhood. Despite aggressive treatment, the prognosis of ATRT patients...
7.
Pan Y, Lai J, Huang W, Peng P, Jung S, Lin S, et al.
Cancer Gene Ther
. 2023 Dec;
31(2):322-333.
PMID: 38057358
Intrahepatic cholangiocarcinoma (iCCA) is a subtype of CCA and has a high mortality rate and a relatively poor prognosis. However, studies focusing on increased cell motility and loss of epithelial...
8.
Lo T, Cheng J, Lee C, Hung J, Lin C, Yeh H, et al.
Dev Cell
. 2023 Nov;
58(22):2447-2459.e5.
PMID: 37989081
Glycosphingolipids (GSLs) display diverse functions during embryonic development. Here, we examined the GSL profiles of extracellular vesicles (EVs) secreted from human embryonic stem cells (hESCs) and investigated their functions in...
9.
Hung T, Yeh C, Hung J, Wu C, Lee C, Yu J, et al.
Am J Cancer Res
. 2023 Nov;
13(10):4811-4821.
PMID: 37970342
In recent studies, there has been growing interest in developing cancer therapeutics targeting Globo H ceramide, which is considered as the most prevalent tumor-associated carbohydrate antigen in epithelial cancers. In...
10.
Tsai H, Kao H, Kuo M, Lin C, Chang C, Chen Y, et al.
Nat Commun
. 2023 Aug;
14(1):5183.
PMID: 37626063
CRISPR-Cas9 genome editing has promising therapeutic potential for genetic diseases and cancers, but safety could be a concern. Here we use whole genomic analysis by 10x linked-read sequencing and optical...