Yeon Gyu Yu
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Explore the profile of Yeon Gyu Yu including associated specialties, affiliations and a list of published articles.
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50
Citations
328
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Recent Articles
11.
Na J, Lee W, Yu Y
Int J Mol Sci
. 2018 Feb;
19(2).
PMID: 29382046
Intrinsically disordered proteins (IDPs) represent approximately 30% of the human genome and play key roles in cell proliferation and cellular signaling by modulating the function of target proteins via protein-protein...
12.
Han S, Ko S, Lee W, Jung S, Yu Y
Sci Rep
. 2017 Aug;
7(1):7577.
PMID: 28790412
G-protein coupled receptors (GPCRs) play indispensable physiological roles in cell proliferation, differentiation, and migration; therefore, identifying the mechanisms by which ligands bind to GPCRs is crucial for developing GPCR-targeting pharmaceutics...
13.
Han S, Baek S, Son T, Lee H, Kim N, Yu Y
Biochem Biophys Res Commun
. 2017 Apr;
487(1):103-108.
PMID: 28392399
Human lysophosphatidic acid receptor 2 (LPA), a member of the G-protein coupled receptor family, mediates lysophosphatidic acid (LPA)-dependent signaling by recruiting various G proteins. Particularly, it is directly implicated in...
14.
Yoon H, Kim H, Mikami B, Yu Y, Lee H
Extremophiles
. 2016 Jul;
20(5):723-31.
PMID: 27377296
Oligopeptide-binding proteins (Opps) are part of the ATP-binding cassette system, playing a crucial role in nutrient uptake and sensing the external environment in bacteria, including hyperthermophiles. Opps serve as a...
15.
Na J, Lee W, Kim Y, Jeong C, Song S, Cha S, et al.
Biochem Biophys Res Commun
. 2016 Jun;
477(2):181-7.
PMID: 27297113
Nucleolar phosphoprotein 140 (Nopp140) is a nucleolar protein, more than 80% of which is disordered. Previous studies have shown that the C-terminal region of Nopp140 (residues 568-596) interacts with protein...
16.
Kim M, Kim H, Son S, Yoon H, Lim Y, Lee J, et al.
Proc Natl Acad Sci U S A
. 2016 Apr;
113(18):E2480-8.
PMID: 27099293
DNA-binding repressors are involved in transcriptional repression in many organisms. Disabling a repressor is a crucial step in activating expression of desired genes. Thus, several mechanisms have been identified for...
17.
Kim H, Yoon J, Matsuura A, Na J, Lee W, Kim H, et al.
Proc Natl Acad Sci U S A
. 2015 Sep;
112(40):12372-7.
PMID: 26392564
Intercellular bridges are a conserved feature of spermatogenesis in mammalian germ cells and derive from arresting cell abscission at the final stage of cytokinesis. However, it remains to be fully...
18.
Ju M, Na J, Yu Y, Kim J, Jeong C, Jung S
Mol Immunol
. 2015 Jul;
67(2 Pt B):350-6.
PMID: 26153451
In contrast to the glycosylated IgG antibodies secreted by human plasma cells, the aglycosylated IgG antibodies produced by bacteria are unable to bind FcγRs expressed on the surface of immune...
19.
Kim J, Yang Y, Song S, Na J, Oh K, Jeong C, et al.
Biophys J
. 2014 Oct;
107(7):1601-8.
PMID: 25296312
In Alzheimer's disease, cytochrome c-dependent apoptosis is a crucial pathway in neuronal cell death. Although beta-amyloid (Aβ) oligomers are known to be the neurotoxins responsible for neuronal cell death, the...
20.
Han S, Na J, Lee W, Park D, Oh J, Yoon S, et al.
Protein Sci
. 2014 Oct;
23(12):1800-7.
PMID: 25283538
Difficulties in the extraction of membrane proteins from cell membrane and their solubilization in native conformations have hindered their structural and biochemical analysis. To overcome these difficulties, an amphipathic polypeptide...