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Yee-Joo Tan

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Articles 93
Citations 8125
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Recent Articles
1.
Cao Y, Lai K, Fu K, Kuo C, Tan Y, Yu L, et al.
Foods . 2024 Oct; 13(20). PMID: 39456336
Papaya leaves have been used as food and traditional herbs for the treatment of cancer, diabetes, asthma, and virus infections, but the active principle has not been understood. We hypothesized...
2.
Cao Y, Tan Y, Huang D
Int J Mol Sci . 2024 Oct; 25(19). PMID: 39409020
5,6-dihydroxyflavone (5,6-DHF), a flavonoid that possesses potential anti-inflammatory and antioxidant activities owing to its special catechol motif on the A ring. However, its function and mechanism of action against inflammation...
3.
Paul S, Patwa S, Tan Y
J Viral Hepat . 2023 Aug; 30(11):870-878. PMID: 37525419
Over 250 million people are living with chronic infection caused by the hepatitis B virus (HBV). HBV has three surface proteins, namely small (SHBs), medium (MHBs) and large (LHBs), and...
4.
Malisheni M, Chong C, Murali T, Purushotorman K, Qian X, Laiman A, et al.
Pathogens . 2023 Jan; 12(1). PMID: 36678399
Several human monoclonal Abs for treating Influenza have been evaluated in clinical trials with limited success despite demonstrating superiority in preclinical animal models including mice. To conduct efficacy studies in...
5.
Blasiak A, Truong A, Remus A, Hooi L, Seah S, Wang P, et al.
NPJ Digit Med . 2022 Jun; 5(1):83. PMID: 35773329
IDentif.AI-x, a clinically actionable artificial intelligence platform, was used to rapidly pinpoint and prioritize optimal combination therapies against COVID-19 by pairing a prospective, experimental validation of multi-drug efficacy on a...
6.
Lim Z, Mohd-Ismail N, Png E, Sze C, Lin Q, Hong W, et al.
Int J Mol Sci . 2022 May; 23(9). PMID: 35563518
Hepatitis B virus (HBV) infection persists as a major global health problem despite the availability of HBV vaccines for disease prevention. However, vaccination rates remains low in some regions of...
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Lam J, Khan A, Cornell T, Chia T, Dress R, Yeow W, et al.
ACS Nano . 2021 Oct; 15(10):15754-15770. PMID: 34618423
Multiple successful vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are urgently needed to address the ongoing coronavirus disease 2019 (Covid-19) pandemic. In the present work, we describe a...
9.
Ng K, Mohd-Ismail N, Tan Y
Vaccines (Basel) . 2021 Mar; 9(2). PMID: 33672450
In the midst of the unceasing COVID-19 pandemic, the identification of immunogenic epitopes in the SARS-CoV-2 spike (S) glycoprotein plays a vital role in the advancement and development of intervention...
10.
Bert N, Clapham H, Tan A, Chia W, Tham C, Lim J, et al.
J Exp Med . 2021 Mar; 218(5). PMID: 33646265
The efficacy of virus-specific T cells in clearing pathogens involves a fine balance between antiviral and inflammatory features. SARS-CoV-2-specific T cells in individuals who clear SARS-CoV-2 without symptoms could reveal...