Yasuko Yamamoto
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Explore the profile of Yasuko Yamamoto including associated specialties, affiliations and a list of published articles.
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78
Citations
1054
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Recent Articles
1.
Hasegawa M, Kunisawa K, Wulaer B, Kubota H, Kurahashi H, Sakata T, et al.
Br J Pharmacol
. 2024 Dec;
182(7):1466-1486.
PMID: 39658392
Background And Purpose: Alterations in tryptophan-kynurenine (TRP-KYN) pathway are implicated in major depressive disorder (MDD). α7 nicotinic acetylcholine (α7nACh) receptor regulates the hypothalamic-pituitary-adrenal (HPA) axis. We have shown that deficiency...
2.
Hanyuda A, Raita Y, Ninomiya T, Hashimoto K, Takada N, Sato K, et al.
Invest Ophthalmol Vis Sci
. 2024 Nov;
65(13):44.
PMID: 39565301
Purpose: The purpose of this study was to investigate biologically meaningful endotypes of open-angle glaucoma (OAG) by applying unsupervised machine learning to plasma metabolites. Methods: This retrospective longitudinal cohort study...
3.
Hasegawa M, Niijima M, Kunisawa K, Teshigawara T, Kubota H, Fujigaki S, et al.
Biochem Biophys Res Commun
. 2024 Nov;
737:150922.
PMID: 39486137
Maternal immune activation (MIA) is recognized as one of the significant environmental risk factors for neuropsychiatric disorders such as schizophrenia in adult offspring. However, the pathophysiological mechanisms remain unknown. The...
4.
Okazawa-Sakai M, Sakai S, Hyodo I, Horasawa S, Sawada K, Fujisawa T, et al.
J Gynecol Oncol
. 2024 Oct;
PMID: 39453391
Objective: To investigate an association between the gut microbiome and efficacy of poly(ADP-ribose) polymerase inhibitors (PARPi) in ovarian cancer. Methods: This study conducted fecal microbiome analysis (16S rRNA gene sequencing)...
5.
Yamamoto Y, Goto N, Kambara K, Fujigaki S, Fujigaki H, Takemura M, et al.
Ann Clin Biochem
. 2024 Oct;
:45632241297873.
PMID: 39439179
Objectives: Reports have shown that the kynurenine pathway, one of the pathways by which tryptophan is metabolized, is activated in patients with diffuse large B-cell lymphoma (DLBCL). Activation of the...
6.
Yamamoto Y, Taniguchi T, Shimazaki A
Biomolecules
. 2024 Sep;
14(9).
PMID: 39334813
Rotenone is a mitochondrial complex I inhibitor that causes retinal degeneration. A study of a rat model of rotenone-induced retinal degeneration suggested that this model is caused by indirect postsynaptic...
7.
Mizutani A, Nishikawa T, Fujigaki H, Yamamoto Y, Saito K, Hatayama S, et al.
J Nutr Sci Vitaminol (Tokyo)
. 2024 Jun;
70(3):185-192.
PMID: 38945883
Niacin is a cofactor in many biological reactions related to energy metabolism, redox reactions, DNA repair and longevity. Although it has been considered that increasing energy expenditure increases NAD consumption,...
8.
Kunisawa K, Hara M, Yoshidomi K, Kon Y, Yamamoto Y, Fujigaki S, et al.
Mol Neurobiol
. 2024 Jun;
62(1):109-122.
PMID: 38829509
Demyelinating diseases including multiple sclerosis (MS) are chronic inflammatory diseases of the central nervous system. Indoleamine 2,3-dioxygenase 2 (Ido2) is a recently identified as catalytic enzyme involved in the rate-limiting...
9.
Mizutani A, Goto C, Fujigaki H, Yamamoto Y, Saito K, Hatayama S, et al.
J Nutr Sci Vitaminol (Tokyo)
. 2024 Feb;
70(1):1-8.
PMID: 38417847
Niacin is involved in many biological reactions relating energy metabolism, redox reactions, DNA repair and longevity. Since niacin deficiency has been reported in alcoholic patients, and niacin coenzyme NAD is...
10.
Morishita T, Takemura M, Hayashi M, Saito K, Yamamoto Y, Tsurumi H, et al.
BMJ Open
. 2024 Feb;
14(2):e077720.
PMID: 38307527
Purpose: The increased global burden of non-communicable diseases and mental disorders is an urgent health challenge for countries around the entire world, especially those experiencing super-ageing societies, where over 21%...