Yasuhiro Onogi
Overview
Explore the profile of Yasuhiro Onogi including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
258
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Recent Articles
1.
Wada T, Takeda Y, Okekawa A, Komatsu G, Iwasa Y, Onogi Y, et al.
Sci Rep
. 2024 Oct;
14(1):23829.
PMID: 39394459
The platelet-derived growth factor (PDGF) family contributes to the progression of steatohepatitis; however, changes in and the characteristics of isoform-specific expression remain unclear. Since diabetes is a major driver of...
2.
Platelet-derived growth factor signaling in pericytes promotes hypothalamic inflammation and obesity
Okekawa A, Wada T, Onogi Y, Takeda Y, Miyazawa Y, Sasahara M, et al.
Mol Med
. 2024 Feb;
30(1):21.
PMID: 38317079
Background: Pericytes are a vital component of the blood-brain barrier, and their involvement in acute inflammation was recently suggested. However, it remains unclear whether pericytes contribute to hypothalamic chronic inflammation...
3.
Liu X, Khalil A, Muthukumarasamy U, Onogi Y, Yan X, Singh I, et al.
BMC Biol
. 2023 Jul;
21(1):150.
PMID: 37403071
Background: Biological aging is an important factor leading to the development of pathologies associated with metabolic dysregulation, including type 2 diabetes, cancer, cardiovascular and neurodegenerative diseases. Telomere length, a central...
4.
Wada T, Miyazawa Y, Ikurumi M, Fuse K, Okekawa A, Onogi Y, et al.
Nutr Metab (Lond)
. 2023 Feb;
20(1):10.
PMID: 36774476
Aim: MC903 is a synthetic derivative of vitamin D3 that has been designed to diminish its impact on calcium metabolism and is clinically used as a transdermal reagent for psoriasis....
5.
Tsuneki H, Maeda T, Takata S, Sugiyama M, Otsuka K, Ishizuka H, et al.
Cell Rep
. 2022 Oct;
41(3):111497.
PMID: 36261021
Non-alcoholic steatohepatitis (NASH) occasionally occurs under obesity; however, factors modulating the natural history of fatty liver disease remain unknown. Since hypothalamic orexin that regulates physical activity and autonomic balance prevents...
6.
Lopez-Gonzales E, Lehmann L, Ruiz-Ojeda F, Hernandez-Bautista R, Altun I, Onogi Y, et al.
Nutrients
. 2022 May;
14(9).
PMID: 35565889
Weight regain after fasting, often exceeding the pre-fasting weight, is a common phenomenon and big problem for the treatment of obesity. Thus, novel interventions maintaining reduced body weight are critically...
7.
Wang J, Onogi Y, Krueger M, Oeckl J, Karlina R, Singh I, et al.
Mol Metab
. 2022 May;
61:101508.
PMID: 35513259
Objective: Brown adipocytes play a key role in maintaining body temperature as well as glucose and lipid homeostasis. However, brown adipocytes need to adapt their thermogenic activity and substrate utilization...
8.
Onogi Y, Ussar S
Trends Endocrinol Metab
. 2022 May;
33(7):493-506.
PMID: 35491296
Brown adipose tissue (BAT) is often considered as a sink for nutrients to generate heat. However, when the complex hormonal and nervous inputs and intracellular signaling networks regulating substrate utilization...
9.
10.
Tanaka T, Wada T, Uno K, Ogihara S, Ie H, Okekawa A, et al.
Diabetologia
. 2021 Apr;
64(7):1660-1673.
PMID: 33796910
Aims/hypothesis: The imbalance between maternal insulin resistance and a relative lack of insulin secretion underlies the pathogenesis of gestational diabetes mellitus (GDM). Alterations in T cell subtypes and increased levels...