Masakiyo Sasahara
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Explore the profile of Masakiyo Sasahara including associated specialties, affiliations and a list of published articles.
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103
Citations
2434
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Recent Articles
1.
Okuno N, Takagi K, Nakajima T, Fujinami H, Hirabayashi K, Sasahara M
Cureus
. 2024 Oct;
16(9):e69907.
PMID: 39439633
Alveolar rhabdomyosarcoma (ARMS) is a malignant tumor with skeletal muscle differentiation that usually occurs in soft tissues of the extremities or trunk. To date, only a few cases of primary...
2.
Wada T, Takeda Y, Okekawa A, Komatsu G, Iwasa Y, Onogi Y, et al.
Sci Rep
. 2024 Oct;
14(1):23829.
PMID: 39394459
The platelet-derived growth factor (PDGF) family contributes to the progression of steatohepatitis; however, changes in and the characteristics of isoform-specific expression remain unclear. Since diabetes is a major driver of...
3.
Platelet-derived growth factor signaling in pericytes promotes hypothalamic inflammation and obesity
Okekawa A, Wada T, Onogi Y, Takeda Y, Miyazawa Y, Sasahara M, et al.
Mol Med
. 2024 Feb;
30(1):21.
PMID: 38317079
Background: Pericytes are a vital component of the blood-brain barrier, and their involvement in acute inflammation was recently suggested. However, it remains unclear whether pericytes contribute to hypothalamic chronic inflammation...
4.
Takashima Y, Yamamoto S, Okuno N, Hamashima T, Dang S, Tran N, et al.
Biochem Biophys Res Commun
. 2023 Apr;
658:27-35.
PMID: 37018886
The beiging of white adipose tissue (WAT) is expected to improve systemic metabolic conditions; however, the regulation and developmental origin of this process remain insufficiently understood. In the present study,...
5.
Nawaz A, Bilal M, Fujisaka S, Kado T, Aslam M, Ahmed S, et al.
Nat Commun
. 2022 Nov;
13(1):7058.
PMID: 36411280
Muscle regeneration requires the coordination of muscle stem cells, mesenchymal fibro-adipogenic progenitors (FAPs), and macrophages. How macrophages regulate the paracrine secretion of FAPs during the recovery process remains elusive. Herein,...
6.
Tsuneki H, Maeda T, Takata S, Sugiyama M, Otsuka K, Ishizuka H, et al.
Cell Rep
. 2022 Oct;
41(3):111497.
PMID: 36261021
Non-alcoholic steatohepatitis (NASH) occasionally occurs under obesity; however, factors modulating the natural history of fatty liver disease remain unknown. Since hypothalamic orexin that regulates physical activity and autonomic balance prevents...
7.
Yamamoto S, Yamamoto S, Akai T, Sasahara M, Kuroda S
Stroke
. 2022 Aug;
53(11):3465-3473.
PMID: 36039752
Background: Moyamoya disease (MMD) is a very specific disorder in terms of spontaneous development of extracranial-to-intracranial collateral circulation through the dura mater, but the underlying mechanisms are unclear. This study...
8.
Nakamura T, Kurosaki K, Kanemoto M, Sasahara M, Ichijo H
J Psychiatry Neurosci
. 2021 Aug;
46(4):E480-E489.
PMID: 34346201
Background: Abnormally high activity in the lateral habenula causes anxiety- or depression-like behaviours in animal experimental models. It has also been reported in humans that excessive stress in early life...
9.
Yoshida N, Yamamoto S, Hamashima T, Okuno N, Okita N, Horikawa S, et al.
Proc Natl Acad Sci U S A
. 2021 May;
118(19).
PMID: 33941693
Along with blood vessels, lymphatic vessels play an important role in the circulation of body fluid and recruitment of immune cells. Postnatal lymphangiogenesis commonly occurs from preexisting lymphatic vessels by...
10.
Tanaka T, Wada T, Uno K, Ogihara S, Ie H, Okekawa A, et al.
Diabetologia
. 2021 Apr;
64(7):1660-1673.
PMID: 33796910
Aims/hypothesis: The imbalance between maternal insulin resistance and a relative lack of insulin secretion underlies the pathogenesis of gestational diabetes mellitus (GDM). Alterations in T cell subtypes and increased levels...