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Yashwant Kumar

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Articles 141
Citations 962
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Recent Articles
1.
Dalal R, Sadhu S, Batra A, Goswami S, Dandotiya J, K V V, et al.
NPJ Biofilms Microbiomes . 2025 Mar; 11(1):44. PMID: 40082467
Gut microbiota-derived metabolites play a crucial role in modulating the inflammatory response in inflammatory bowel disease (IBD). In this study, we identify gut microbiota-derived succinate as a driver of inflammation...
2.
Chawla M, Verma J, Kumari S, Matta T, Senapati T, Babele P, et al.
Microbiol Spectr . 2025 Feb; :e0116924. PMID: 39992161
The key signaling molecules in the bacterial stress-sensing pathway, the alarmone (p)ppGpp and the transcription factor DksA, play a crucial role in bacterial survival during nutritional deprivation and exposure to...
3.
Priya M, Gupta S, Koundal A, Kapoor S, Tiwari S, Kidwai S, et al.
Proc Natl Acad Sci U S A . 2025 Jan; 122(4):e2423114122. PMID: 39841148
Itaconate, an abundant metabolite produced by macrophages upon interferon-γ stimulation, possesses both antibacterial and immunomodulatory properties. Despite its crucial role in immunity and antimicrobial control, its mechanism of action and...
4.
Safwan S, Mehta D, Arora A, Khatol S, Singh M, Rana K, et al.
ACS Infect Dis . 2024 Nov; 10(12):4146-4155. PMID: 39564818
Polymicrobial wound infections caused by Gram-negative bacteria and associated inflammation are challenging to manage, as many antibiotics do not work against these infections. Utilizing adjuvants to repurpose the existing antibiotics...
5.
Singh D, Zhao H, Gupta S, Kumar Y, Kim J, Pawar P
Physiol Plant . 2024 Nov; 176(6):e14618. PMID: 39542838
Glucuronoxylan is present mainly in the dicot of the secondary cell walls, often O-acetylated, which stabilizes cell structure by maintaining interaction with cellulose and other cell wall components. Some members...
6.
Aggarwal H, Gautam J, Gupta S, Das B, Kumar Y, Jagavelu K, et al.
Nutr Res . 2024 Nov; 132:95-111. PMID: 39532058
Oxidative and nitrosative stress play pivotal roles in normal physiological processes and the pathogenesis of metabolic disorders. Previous studies from our lab demonstrated insulin resistance (IR), and dyslipidemia in iNOS...
7.
Khan S, Aggarwal S, Bhatia P, Yadav A, Kumar Y, Veerapu N
Arch Virol . 2024 Oct; 169(11):233. PMID: 39476184
Viruses have undergone evolutionary adaptations to tune their utilization of carbon sources, enabling them to extract specific cellular substrates necessary for their replication. The lack of a reliable cell culture...
8.
Singh R, Bajpai S, Singh A, Sharma P, Kumar Y, Kumar N
Methods Mol Biol . 2024 Oct; 2853:205-234. PMID: 39460923
Increasing demand of protein biotherapeutics produced using Chinese hamster ovary (CHO) cell lines necessitates improvement in the production yield of the bioprocess. Various cell engineering, improved media formulation and process-design ...
9.
Tabrez S, Fatima Z, Akand S, Rahman A, Hameed S, Saleem M, et al.
Parasite Immunol . 2024 Sep; 46(8-9):e13066. PMID: 39310969
Obligate intracellular protozoan parasite, Leishmania donovani, causative agent of visceral leishmaniasis, led to impaired macrophage functions. It is well documented that many of these changes were induced by parasite-mediated reduction...
10.
Kumar Y, Agrawal K, Ojha M, Pushpavanam K
Bioconjug Chem . 2024 Sep; 35(9):1343-1351. PMID: 39223465
The production of recombinant proteins has become a focal point in biotechnology, with potential applications in catalysis, therapeutics, and diagnostics. Before their application, these proteins undergo cumbersome downstream processing, including...