Yashang Lee
Overview
Explore the profile of Yashang Lee including associated specialties, affiliations and a list of published articles.
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21
Citations
570
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Recent Articles
1.
Cirillo P, Asojo O, Khire U, Lee Y, Mootien S, Hegan P, et al.
ACS Med Chem Lett
. 2020 Oct;
11(10):1843-1847.
PMID: 33062162
Human Macrophage Migration Inhibitory Factor (MIF) is a trimeric cytokine implicated in a number of inflammatory and autoimmune diseases and cancer. We previously reported that the dye p425 (Chicago Sky...
2.
Lee Y, Blount K, Dai F, Thompson S, Scher J, Bitterman S, et al.
Clin Exp Nephrol
. 2018 Feb;
22(4):906-916.
PMID: 29453607
Background: Semaphorin 7A (SEMA7A) is an immunomodulating protein implicated in lung and liver fibrosis. In autosomal-dominant polycystic kidney disease (ADPKD), the progressive expansion of renal cysts, inflammation, and subsequent renal...
3.
Ratner E, Zhu Y, Penketh P, Berenblum J, Whicker M, Huang P, et al.
Br J Cancer
. 2016 Mar;
114(7):777-86.
PMID: 26964031
Background: Platinum resistance may be attributable to inherent or acquired proficiency in homologous recombination repair (HRR) in epithelial ovarian cancer (EOC). The objective of this study was to evaluate the...
4.
Yuan A, Lee Y, Choi U, Moeckel G, Karihaloo A
Am J Physiol Renal Physiol
. 2014 Dec;
308(5):F459-72.
PMID: 25537742
Kidney fibrosis is the final common pathway for virtually every type of chronic kidney disease and is a consequence of a prolonged healing response that follows tissue inflammation. Chronic kidney...
5.
Huen S, Huynh L, Marlier A, Lee Y, Moeckel G, Cantley L
J Am Soc Nephrol
. 2014 Nov;
26(6):1334-45.
PMID: 25388222
After kidney ischemia/reperfusion (I/R) injury, monocytes home to the kidney and differentiate into activated macrophages. Whereas proinflammatory macrophages contribute to the initial kidney damage, an alternatively activated phenotype can promote...
6.
Asojo O, Nelson S, Mootien S, Lee Y, Rezende W, Hyman D, et al.
Acta Crystallogr D Biol Crystallogr
. 2014 Jul;
70(Pt 7):1922-33.
PMID: 25004969
Clostridium difficile, a Gram-positive, spore-forming anaerobic bacterium, is the leading cause of infectious diarrhea among hospitalized patients. C. difficile is frequently associated with antibiotic treatment, and causes diseases ranging from...
7.
Tian X, Kim J, Monkley S, Gotoh N, Nandez R, Soda K, et al.
J Clin Invest
. 2014 Feb;
124(3):1098-113.
PMID: 24531545
Podocytes are specialized actin-rich epithelial cells that line the kidney glomerular filtration barrier. The interface between the podocyte and the glomerular basement membrane requires integrins, and defects in either α3...
8.
Lin Z, Ratner E, Whicker M, Lee Y, Sartorelli A
Mol Cancer Res
. 2014 Jan;
12(3):381-393.
PMID: 24413181
Unlabelled: PARP inhibitors exploit synthetic lethality to target epithelial ovarian cancer (EOC) with hereditary BRCA mutations and defects in homologous recombination repair (HRR). However, such an approach is limited to...
9.
Lee Y, Mootien S, Shoen C, DeStefano M, Cirillo P, Asojo O, et al.
Biochem Pharmacol
. 2013 May;
86(2):222-30.
PMID: 23680030
The genus Mycobacterium includes non-pathogenic species such as M. smegmatis, and pathogenic species such as M. tuberculosis, the causative agent of tuberculosis (TB). Treatment of TB requires a lengthy regimen...
10.
Schmidt I, Hall I, Kale S, Lee S, He C, Lee Y, et al.
J Am Soc Nephrol
. 2013 Jan;
24(2):309-19.
PMID: 23291472
Kidney hypoperfusion during episodes of systemic hypotension or after surgical procurement for transplantation can lead to tubular cell death via necrosis and apoptosis, which trigger a series of responses that...