Yariv Houvras
Overview
Explore the profile of Yariv Houvras including associated specialties, affiliations and a list of published articles.
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35
Citations
1596
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Recent Articles
11.
Al Zoughbi W, Fox J, Beg S, Papp E, Hissong E, Ohara K, et al.
Oncologist
. 2021 Jul;
26(11):e1971-e1981.
PMID: 34286887
Background: Characterization of circulating tumor DNA (ctDNA) has been integrated into clinical practice. Although labs have standardized validation procedures to develop single locus tests, the efficacy of on-site plasma-based next-generation...
12.
Weeks O, Bosse G, Oderberg I, Akle S, Houvras Y, Wrighton P, et al.
J Clin Invest
. 2020 Mar;
130(5):2252-2269.
PMID: 32202514
Prenatal alcohol exposure (PAE) affects at least 10% of newborns globally and leads to the development of fetal alcohol spectrum disorders (FASDs). Despite its high incidence, there is no consensus...
13.
Salhi A, Jordan A, Bochaca I, Izsak A, Darvishian F, Houvras Y, et al.
Am J Pathol
. 2020 Mar;
190(5):1108-1117.
PMID: 32142731
Dermal invasion is a hallmark of malignant melanoma. Although the molecular alterations that drive the progression of primary melanoma to metastatic disease have been studied extensively, the early progression of...
14.
DiNapoli S, Martinez-McFaline R, Gribbin C, Wrighton P, Balgobin C, Nelson I, et al.
Nucleic Acids Res
. 2020 Feb;
48(7):e38.
PMID: 32064511
CRISPR/Cas9 has become a powerful tool for genome editing in zebrafish that permits the rapid generation of loss of function mutations and the knock-in of specific alleles using DNA templates...
15.
Nissim S, Leshchiner I, Mancias J, Greenblatt M, Maertens O, Cassa C, et al.
Nat Genet
. 2019 Aug;
51(9):1308-1314.
PMID: 31406347
Pancreatic ductal adenocarcinoma is an aggressive cancer with limited treatment options. Approximately 10% of cases exhibit familial predisposition, but causative genes are not known in most families. We perform whole-genome...
16.
Chaturantabut S, Shwartz A, Evason K, Cox A, LaBella K, Schepers A, et al.
Gastroenterology
. 2019 Jan;
156(6):1788-1804.e13.
PMID: 30641053
Background & Aims: Patients with cirrhosis are at high risk for hepatocellular carcinoma (HCC) and often have increased serum levels of estrogen. It is not clear how estrogen promotes hepatic...
17.
Cox A, Tsomides A, Yimlamai D, Hwang K, Miesfeld J, Galli G, et al.
EMBO J
. 2018 Oct;
37(22).
PMID: 30348863
The Hippo pathway and its nuclear effector Yap regulate organ size and cancer formation. While many modulators of Hippo activity have been identified, little is known about the Yap target...
18.
Venkatesan A, Vyas R, Gramann A, Dresser K, Gujja S, Bhatnagar S, et al.
J Clin Invest
. 2017 Dec;
128(1):294-308.
PMID: 29202482
Oncogenomic studies indicate that copy number variation (CNV) alters genes involved in tumor progression; however, identification of specific driver genes affected by CNV has been difficult, as these rearrangements are...
19.
Kasheta M, Painter C, Moore F, Lobbardi R, Bryll A, Freiman E, et al.
J Exp Med
. 2017 Oct;
214(12):3519-3530.
PMID: 29066577
Regulatory T (T reg) cells are a specialized sublineage of T lymphocytes that suppress autoreactive T cells. Functional studies of T reg cells in vitro have defined multiple suppression mechanisms,...
20.
Anelli V, Villefranc J, Chhangawala S, Martinez-McFaline R, Riva E, Nguyen A, et al.
Elife
. 2017 Mar;
6.
PMID: 28350298
Thyroid cancer is common, yet the sequence of alterations that promote tumor formation are incompletely understood. Here, we describe a novel model of thyroid carcinoma in zebrafish that reveals temporal...