Yanal Ghosheh
Overview
Explore the profile of Yanal Ghosheh including associated specialties, affiliations and a list of published articles.
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35
Citations
1677
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Recent Articles
11.
Saigusa R, Vallejo J, Gulati R, Suthahar S, Suryawanshi V, Alimadadi A, et al.
Int J Mol Sci
. 2022 Sep;
23(17).
PMID: 36077273
Despite the decades-old knowledge that males and people with diabetes mellitus (DM) are at increased risk for coronary artery disease (CAD), the reasons for this association are only partially understood....
12.
Yuan B, Zhou X, Suzuki K, Ramos-Mandujano G, Wang M, Tehseen M, et al.
Nat Commun
. 2022 Sep;
13(1):5291.
PMID: 36075901
No abstract available.
13.
Vallejo J, Saigusa R, Gulati R, Suthahar S, Suryawanshi V, Alimadadi A, et al.
BMC Biol
. 2022 Aug;
20(1):193.
PMID: 36045343
Background: Cryopreserved peripheral blood mononuclear cells (PBMCs) are frequently collected and provide disease- and treatment-relevant data in clinical studies. Here, we developed combined protein (40 antibodies) and transcript single-cell (sc)RNA...
14.
Saigusa R, Roy P, Freuchet A, Gulati R, Ghosheh Y, Suthahar S, et al.
Nat Cardiovasc Res
. 2022 Aug;
1(5):462-475.
PMID: 35990517
Atherosclerosis is accompanied by a CD4 T cell response to apolipoprotein B (APOB). Major Histocompatibility Complex (MHC)-II tetramers can be used to isolate antigen-specific CD4 T cells by flow sorting....
15.
Yuan B, Zhou X, Suzuki K, Ramos-Mandujano G, Wang M, Tehseen M, et al.
Nat Commun
. 2022 Jun;
13(1):3646.
PMID: 35752626
The diverse functions of WASP, the deficiency of which causes Wiskott-Aldrich syndrome (WAS), remain poorly defined. We generated three isogenic WAS models using patient induced pluripotent stem cells and genome...
16.
Pattarabanjird T, Wilson J, Erickson L, Workman L, Qiao H, Ghosheh Y, et al.
Front Cardiovasc Med
. 2022 Jan;
8:791028.
PMID: 35097011
Recent studies have suggested that IgE sensitization to α-gal is associated with coronary artery disease (CAD). However, the B cell subtype(s) responsible for production of IgE to α-gal and mechanisms...
17.
Orecchioni M, Kobiyama K, Winkels H, Ghosheh Y, McArdle S, Mikulski Z, et al.
Science
. 2022 Jan;
375(6577):214-221.
PMID: 35025664
Atherosclerosis is an inflammatory disease of the artery walls and involves immune cells such as macrophages. Olfactory receptors (OLFRs) are G protein–coupled chemoreceptors that have a central role in detecting...
18.
Winkels H, Ghosheh Y, Kobiyama K, Kiosses W, Orecchioni M, Ehinger E, et al.
J Immunol
. 2021 Nov;
207(11):2720-2732.
PMID: 34740961
Double-positive CD4CD8αβ (DP) cells are thought to reside as T cell progenitors exclusively within the thymus. We recently discovered an unexpected CD4 and CD8αβ immune cell population in healthy and...
19.
Tillie R, de Bruijn J, Perales-Paton J, Temmerman L, Ghosheh Y, van Kuijk K, et al.
Front Cell Dev Biol
. 2021 Aug;
9:695684.
PMID: 34458258
Background: The protein 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) is a key stimulator of glycolytic flux. Systemic, partial PFKFB3 inhibition previously decreased total plaque burden and increased plaque stability. However, it is unclear which...
20.
Navia-Pelaez J, Choi S, Capettini L, Xia Y, Gonen A, Agatisa-Boyle C, et al.
J Exp Med
. 2021 May;
218(7).
PMID: 33970188
Neuroinflammation is a major component in the transition to and perpetuation of neuropathic pain states. Spinal neuroinflammation involves activation of TLR4, localized to enlarged, cholesterol-enriched lipid rafts, designated here as...