Christopher P Durant
Overview
Explore the profile of Christopher P Durant including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
237
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0
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Recent Articles
1.
Chatterjee N, Komaravolu R, Durant C, Wu R, McSkimming C, Drago F, et al.
Int J Mol Sci
. 2024 Mar;
25(5).
PMID: 38474140
Monocytes are associated with human cardiovascular disease progression. Monocytes are segregated into three major subsets: classical (cMo), intermediate (iMo), and nonclassical (nMo). Recent studies have identified heterogeneity within each of...
2.
Iqneibi S, Saigusa R, Khan A, Oliaeimotlagh M, Suthahar S, Kumar S, et al.
Front Immunol
. 2023 Oct;
14:1239148.
PMID: 37828989
Coronary artery disease (CAD) is a major cause of death worldwide. The role of CD8+ T cells in CAD is unknown. Recent studies suggest a breakdown of tolerance in atherosclerosis,...
3.
Vallejo J, Saigusa R, Gulati R, Suthahar S, Suryawanshi V, Alimadadi A, et al.
BMC Biol
. 2022 Oct;
20(1):237.
PMID: 36266696
No abstract available.
4.
Saigusa R, Vallejo J, Gulati R, Suthahar S, Suryawanshi V, Alimadadi A, et al.
Int J Mol Sci
. 2022 Sep;
23(17).
PMID: 36077273
Despite the decades-old knowledge that males and people with diabetes mellitus (DM) are at increased risk for coronary artery disease (CAD), the reasons for this association are only partially understood....
5.
Vallejo J, Saigusa R, Gulati R, Suthahar S, Suryawanshi V, Alimadadi A, et al.
BMC Biol
. 2022 Aug;
20(1):193.
PMID: 36045343
Background: Cryopreserved peripheral blood mononuclear cells (PBMCs) are frequently collected and provide disease- and treatment-relevant data in clinical studies. Here, we developed combined protein (40 antibodies) and transcript single-cell (sc)RNA...
6.
Saigusa R, Roy P, Freuchet A, Gulati R, Ghosheh Y, Suthahar S, et al.
Nat Cardiovasc Res
. 2022 Aug;
1(5):462-475.
PMID: 35990517
Atherosclerosis is accompanied by a CD4 T cell response to apolipoprotein B (APOB). Major Histocompatibility Complex (MHC)-II tetramers can be used to isolate antigen-specific CD4 T cells by flow sorting....
7.
Saigusa R, Durant C, Suryawanshi V, Ley K
Methods Mol Biol
. 2022 Mar;
2419:765-778.
PMID: 35238000
The transcriptomic information obtained by single cell RNA sequencing (scRNA-seq) can be supplemented by information on the cell surface phenotype by using oligonucleotide-tagged monoclonal antibodies (scAb-Seq). This is of particular...
8.
Orecchioni M, Kobiyama K, Winkels H, Ghosheh Y, McArdle S, Mikulski Z, et al.
Science
. 2022 Jan;
375(6577):214-221.
PMID: 35025664
Atherosclerosis is an inflammatory disease of the artery walls and involves immune cells such as macrophages. Olfactory receptors (OLFRs) are G protein–coupled chemoreceptors that have a central role in detecting...
9.
Navia-Pelaez J, Choi S, Capettini L, Xia Y, Gonen A, Agatisa-Boyle C, et al.
J Exp Med
. 2021 May;
218(7).
PMID: 33970188
Neuroinflammation is a major component in the transition to and perpetuation of neuropathic pain states. Spinal neuroinflammation involves activation of TLR4, localized to enlarged, cholesterol-enriched lipid rafts, designated here as...
10.
Ehinger E, Ghosheh Y, Pramod A, Lin J, Hanna D, Mueller K, et al.
Cardiovasc Res
. 2020 Jul;
117(4):1166-1177.
PMID: 32658258
Aims: During virally suppressed chronic HIV infection, persistent inflammation contributes to the development of cardiovascular disease (CVD), a major comorbidity in people living with HIV (LWH). Classical blood monocytes (CMs)...