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Yan Chak Li

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Recent Articles
1.
McDonough C, Li Y, Vangeepuram N, Liu B, Pandey G
JMIR Public Health Surveill . 2024 Nov; 10:e69136. PMID: 39602802
[This corrects the article DOI: 10.2196/53330.].
2.
Sekar J, Li Y, Schlessinger A, Pandey G
NPJ Syst Biol Appl . 2024 Oct; 10(1):113. PMID: 39362876
Interactions between protein kinases and their substrates are critical for the modulation of complex signaling pathways. Currently, there is a large amount of information available about kinases and their substrates...
3.
Herrington N, Li Y, Stein D, Pandey G, Schlessinger A
PLoS Comput Biol . 2024 Jul; 20(7):e1012302. PMID: 39046952
Protein kinase function and interactions with drugs are controlled in part by the movement of the DFG and ɑC-Helix motifs that are related to the catalytic activity of the kinase....
4.
McDonough C, Li Y, Vangeepuram N, Liu B, Pandey G
JMIR Public Health Surveill . 2024 Apr; 10:e53330. PMID: 38666756
Background: The prevalence of type 2 diabetes mellitus (DM) and pre-diabetes mellitus (pre-DM) has been increasing among youth in recent decades in the United States, prompting an urgent need for...
5.
Herrington N, Stein D, Li Y, Pandey G, Schlessinger A
bioRxiv . 2023 Sep; PMID: 37693436
Significance Statement: Greater abundance of kinase structural data in inactive conformations, currently lacking in structural databases, would improve our understanding of how protein kinases function and expand drug discovery and...
6.
McDonough C, Li Y, Vangeepuram N, Liu B, Pandey G
medRxiv . 2023 Aug; PMID: 37577465
The prevalence of type 2 diabetes mellitus (DM) and prediabetes (preDM) is rapidly increasing among youth, posing significant health and economic consequences. To address this growing concern, we created the...
7.
Li Y, Wang L, Law J, Murali T, Pandey G
Bioinform Adv . 2022 Sep; 2(1):vbac065. PMID: 36158455
Motivation: Integrating multimodal data represents an effective approach to predicting biomedical characteristics, such as protein functions and disease outcomes. However, existing data integration approaches do not sufficiently address the heterogeneous...
8.
Li Y, Wang L, Law J, Murali T, Pandey G
bioRxiv . 2022 Aug; PMID: 35923321
Motivation: Integrating multimodal data represents an effective approach to predicting biomedical characteristics, such as protein functions and disease outcomes. However, existing data integration approaches do not sufficiently address the heterogeneous...