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Y van Kooyk

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Articles 71
Citations 3557
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Recent Articles
1.
Bouma R, Nijen Twilhaar M, Brink H, Affandi A, Mesquita B, Olesek K, et al.
Int J Pharm . 2024 May; 660:124254. PMID: 38795934
Cancer vaccines can be utilized in combination with checkpoint inhibitors to optimally stimulate the anti-tumor immune response. Uptake of vaccine antigen by antigen presenting cells (APCs) is a prerequisite for...
2.
Keumatio Doungstop B, van Vliet S, Van Ree R, de Jong E, van Kooyk Y
Trends Immunol . 2021 May; 42(7):635-648. PMID: 34052120
Respiratory allergic disorders are a global public health problem that are responsible for substantial morbidity and healthcare expenditure. Despite the availability of allergen immunotherapy (AIT), its efficacy is suboptimal and...
3.
Grabowska J, Affandi A, van Dinther D, Nijen Twilhaar M, Olesek K, Hoogterp L, et al.
J Control Release . 2021 Jan; 331:309-320. PMID: 33493613
Cancer vaccines aim to efficiently prime cytotoxic CD8 T cell responses which can be achieved by vaccine targeting to dendritic cells. CD169 macrophages have been shown to transfer antigen to...
4.
Kraal T, Lubbers J, van den Bekerom M, Alessie J, van Kooyk Y, Eygendaal D, et al.
J Exp Orthop . 2020 Nov; 7(1):91. PMID: 33205235
Purpose: The pathophysiology of frozen shoulders is a complex and multifactorial process. The purpose of this review is to scope the currently available knowledge of the pathophysiology of frozen shoulders....
5.
Li R, van Vliet S, van Kooyk Y
Curr Opin Biotechnol . 2017 Nov; 51:24-31. PMID: 29175707
Glycans play a crucial role to discern between self and foreign entities by providing key recognition elements for C-type lectin receptors (CLRs) and Siglec receptors expressed on immune cells. The...
6.
Garcia-Vallejo J, Ilarregui J, Kalay H, Chamorro S, Koning N, Unger W, et al.
J Exp Med . 2014 Jun; 211(7):1465-83. PMID: 24935259
Myelin oligodendrocyte glycoprotein (MOG), a constituent of central nervous system myelin, is an important autoantigen in the neuroinflammatory disease multiple sclerosis (MS). However, its function remains unknown. Here, we show...
7.
de Kivit S, Saeland E, Kraneveld A, van de Kant H, Schouten B, Van Esch B, et al.
Allergy . 2012 Jan; 67(3):343-52. PMID: 22229637
Background: Prebiotic galacto- and fructo-oligosaccharides (scGOS/lcFOS) resembling non-digestible oligosaccharides in human milk reduce the development of atopic disorders. However, the underlying mechanisms are still unclear. Galectins are soluble-type lectins recognizing...
8.
Appelmelk B, den Dunnen J, Driessen N, Ummels R, Pak M, Nigou J, et al.
Cell Microbiol . 2007 Dec; 10(4):930-44. PMID: 18070119
Pathogenic mycobacteria have the ability to persist in phagocytic cells and to suppress the immune system. The glycolipid lipoarabinomannan (LAM), in particular its mannose cap, has been shown to inhibit...
9.
Paessens L, Fluitsma D, van Kooyk Y
J Pathol . 2007 Nov; 214(1):96-103. PMID: 17973243
Only a small proportion of thymocytes survive T cell selection in the thymus and leave the thymus as mature T cells. The vast majority of thymocytes undergo cell death during...
10.
Geijtenbeek T, van Kooyk Y
Curr Top Microbiol Immunol . 2003 Jun; 276:31-54. PMID: 12797442
The dendritic cell (DC)-specific HIV-1 receptor DC-SIGN plays a key-role in the dissemination of HIV-1 by DCs. DC-SIGN captures HIV-1 at sites of entry, enabling its transport to lymphoid tissues,...