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Y Sekimori

Explore the profile of Y Sekimori including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 171
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Recent Articles
1.
Igawa T, Tsunoda H, Tachibana T, Maeda A, Mimoto F, Moriyama C, et al.
Protein Eng Des Sel . 2010 Feb; 23(5):385-92. PMID: 20159773
Fc engineering to increase the binding affinity of IgG antibodies to FcRn has been reported to reduce the elimination of IgG antibodies. Herein, we present a novel non-FcRn-dependent approach to...
2.
Ohtomo T, Kawata H, Sekimori Y, Shimizu K, Kishima H, Moriuchi S, et al.
Anticancer Res . 1999 Jan; 18(6A):4311-5. PMID: 9891484
A humanized ONS-M21 antibody (hM21) against human medulloblastoma and glioma cells was engineered as a single-chain Fv fragment (scFv), and its ability to internalize into tumor cells was evaluated by...
3.
Shimizu K, Park K, Tamura K, Kishima H, Kawata H, Yoshimura Y, et al.
Cancer Lett . 1998 Jun; 127(1-2):171-6. PMID: 9619874
In order to evaluate the targeting potential of mouse monoclonal antibody ONS-M21 recognizing a human astrocytoma- and medulloblastoma-associated antigen, the internalization ability of this antibody and the selective cytotoxicity in...
4.
Yasukawa K, Saito T, Fukunaga T, Sekimori Y, Koishihara Y, Fukui H, et al.
J Biochem . 1990 Oct; 108(4):673-6. PMID: 2292596
An immunosorbent assay system to detect genetically engineered IL-6 receptor (IL-6R) was established, whereby soluble IL-6 receptor (sIL-6R) was detected in the culture medium when sIL-6R cDNA was transfected into...