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Y Frobert

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Articles 73
Citations 789
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Recent Articles
1.
Frobert Y, Grassi J
Methods Mol Biol . 2012 Nov; 10:65-78. PMID: 23150296
The production of large quantities of monoclonal antibodies (MAbs) of predetermined specificity has been rendered possible by the pioneering work of Köhler and Milstein (1). These workers have shown that...
2.
Frobert Y, Grassi J
Methods Mol Biol . 2012 Feb; 80:65-78. PMID: 22351199
The production of large quantities of monoclonal antibodies (MAbs) of predetermined specificity has been rendered possible by the pioneering work of Köhler and Milstein (1). These workers have shown that...
3.
Essono S, Frobert Y, Grassi J, Creminon C, Boquet D
J Immunol Methods . 2003 Sep; 279(1-2):251-66. PMID: 12969565
The amplification of variable regions of immunoglobulins by reverse transcription polymerase chain reaction (RT-PCR) has become an invaluable technique either for the cloning of monoclonal antibodies (mAbs), or for the...
4.
Ford M, Burton L, Li H, Graham C, Frobert Y, Grassi J, et al.
Neuroscience . 2002 May; 111(3):533-51. PMID: 12031342
Expression of the normal cellular form of prion protein is both necessary and rate-limiting in the spread of prion disease, yet its cellular expression in vivo is poorly understood. To...
5.
Grassi J, Comoy E, Simon S, Creminon C, Frobert Y, Trapmann S, et al.
Vet Rec . 2001 Dec; 149(19):577-82. PMID: 11730165
The efficacy of a rapid test for detecting PrP(Sc) in central nervous system tissue was evaluated for the postmortem diagnosis of BSE at different times during the course of the...
6.
Thielen C, Melot F, Jolois O, Leclercq F, Tsunoda R, Frobert Y, et al.
Cell Tissue Res . 2001 Oct; 306(1):49-55. PMID: 11683181
As interaction of cellular prion protein (PrPc) and the infectious agent (PrPres) appears to be a crucial pathogenic step promoted by homology, variation in PrPc isoforms on bovine immune cells...
7.
Masson C, Menaa F, Frobert Y, Radicella J, Angulo J
Radiat Res . 2001 Oct; 156(5 Pt 1):535-44. PMID: 11604067
Ionizing radiation elicits a genetic response in human cells that allows cell survival. The human KIN (also known as KIN17) gene encodes a 45-kDa nuclear DNA-binding protein that participates in...
8.
Vincent B, Paitel E, Saftig P, Frobert Y, Hartmann D, De Strooper B, et al.
J Biol Chem . 2001 Jul; 276(41):37743-6. PMID: 11477090
We showed previously that PrPc undergoes constitutive and phorbol ester-regulated cleavage inside the 106-126 toxic domain of the protein, leading to the production of a fragment referred to as N1....
9.
Grassi J, Creminon C, Frobert Y, Fretier P, Turbica I, Rezaei H, et al.
Arch Virol Suppl . 2001 Feb; (16):197-205. PMID: 11214923
The aim of this work was to establish an immunological test suitable for specifically detecting PrPres in tissues from animals or humans developing TSEs. We chose to use as detection...
10.
Sagot M, Wijkhuisen A, Creminon C, Tymciu S, Frobert Y, Turbica I, et al.
Mol Immunol . 2000 Nov; 37(8):423-33. PMID: 11090877
Monoclonal antibody (mAb) PS12, obtained using the complementary peptide methodology, mimics the neuropeptide substance P (SP) in recognizing the SP-binding domain of the neurokinin-1 receptor (NK1R) and eliciting production of...