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Xueying C Li

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Articles 8
Citations 123
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Recent Articles
1.
Gandara L, Jacoby R, Laurent F, Spatuzzi M, Vlachopoulos N, Borst N, et al.
Science . 2024 Oct; 386(6720):446-453. PMID: 39446951
Insect biomass is declining globally, likely driven by climate change and pesticide use, yet systematic studies on the effects of various chemicals remain limited. In this work, we used a...
2.
Li X, Srinivasan V, Laiker I, Misunou N, Frankel N, Pallares L, et al.
Mol Biol Evol . 2024 Aug; 41(8). PMID: 39117360
Understanding the evolutionary potential of mutations in gene regulatory networks is essential to furthering the study of evolution and development. However, in multicellular systems, genetic manipulation of regulatory networks in...
3.
Li X, Gandara L, Ekelof M, Richter K, Alexandrov T, Crocker J
Nat Commun . 2024 May; 15(1):4551. PMID: 38811562
Although the effects of genetic and environmental perturbations on multicellular organisms are rarely restricted to single phenotypic layers, our current understanding of how developmental programs react to these challenges remains...
4.
Li X, Fuqua T, van Breugel M, Crocker J
Philos Trans R Soc Lond B Biol Sci . 2023 Apr; 378(1877):20220054. PMID: 37004721
Rapid enhancer and slow promoter evolution have been demonstrated through comparative genomics. However, it is not clear how this information is encoded genetically and if this can be used to...
5.
Li X, Fay J
G3 (Bethesda) . 2019 Sep; 9(11):3595-3600. PMID: 31519745
Under the model of micromutationism, phenotypic divergence between species is caused by accumulation of many small-effect changes. While mapping the causal changes to single nucleotide resolution could be difficult for...
6.
Baker E, Peris D, Moriarty R, Li X, Fay J, Hittinger C
Sci Adv . 2019 Feb; 5(1):eaav1869. PMID: 30729163
A growing body of research suggests that the mitochondrial genome (mtDNA) is important for temperature adaptation. In the yeast genus , species have diverged in temperature tolerance, driving their use...
7.
Li X, Peris D, Hittinger C, Sia E, Fay J
Sci Adv . 2019 Feb; 5(1):eaav1848. PMID: 30729162
Genetic analysis of phenotypic differences between species is typically limited to interfertile species. Here, we conducted a genome-wide noncomplementation screen to identify genes that contribute to a major difference in...
8.
Li X, Fay J
Genome Biol Evol . 2017 Apr; 9(5):1120-1129. PMID: 28431042
Gene regulation is a ubiquitous mechanism by which organisms respond to their environment. While organisms are often found to be adapted to the environments they experience, the role of gene...