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Xuejian Kong

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Articles 6
Citations 321
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Recent Articles
1.
Wang H, Xie L, Guo H, Li L, Chen S, Fan Y, et al.
Cell Biosci . 2024 Jul; 14(1):92. PMID: 39004750
Background: N-Methyladenosine (mA) is an abundant modification of transcripts regulating mRNA structure and translation efficiency. However, the characteristics and biological functions of mRNA mA modification in adult hippocampal neurogenesis remain...
2.
Li Q, Liu H, Li L, Guo H, Xie Z, Kong X, et al.
Cell Biosci . 2023 Oct; 13(1):183. PMID: 37779199
Background: N-methylguanosine (mG) is one of the most conserved modifications in nucleosides impacting mRNA export, splicing, and translation. However, the precise function and molecular mechanism of internal mRNA mG methylation...
3.
Gong Z, Huang J, Xu B, Ou Z, Zhang L, Lin X, et al.
J Neuroinflammation . 2019 Mar; 16(1):62. PMID: 30871577
Background: Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by an abnormal accumulation of amyloid-β (Aβ) plaques, neuroinflammation, and impaired neurogenesis. Urolithin A (UA), a gut-microbial metabolite of ellagic...
4.
Kong X, Gong Z, Zhang L, Sun X, Ou Z, Xu B, et al.
Brain Behav Immun . 2019 Feb; 79:159-173. PMID: 30763768
Neuroinflammation, considered as a pathological hallmark of Alzheimer's disease (AD), has been demonstrated to affect hippocampal neurogenesis and cognitive function. Interleukin-6 (IL-6) is a proinflammatory cytokine known to modulate neurogenesis....
5.
Ou Z, Kong X, Sun X, He X, Zhang L, Gong Z, et al.
Brain Behav Immun . 2017 Dec; 69:351-363. PMID: 29253574
Alzheimer'sdisease(AD) is characterized by deposition of amyloid-β (Aβ)plaques, neurofibrillary tangles, andneuronal loss, accompaniedbyneuroinflammation. Neuroinflammatoryprocesses are thought to contribute toAD pathophysiology. Metformin has been reported to have anti-inflammatory efficacy. However, whether...
6.
Zhang X, He X, Li Q, Kong X, Ou Z, Zhang L, et al.
Stem Cell Reports . 2017 May; 8(5):1256-1269. PMID: 28494938
Although valproic acid (VPA), has been shown to induce neuronal differentiation of neural stem cells (NSCs), the underlying mechanisms remain poorly understood. Here we investigated if and how mammalian target...