Aiguo Xuan
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Explore the profile of Aiguo Xuan including associated specialties, affiliations and a list of published articles.
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32
Citations
754
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Recent Articles
1.
Wang H, Xie L, Guo H, Li L, Chen S, Fan Y, et al.
Cell Biosci
. 2024 Jul;
14(1):92.
PMID: 39004750
Background: N-Methyladenosine (mA) is an abundant modification of transcripts regulating mRNA structure and translation efficiency. However, the characteristics and biological functions of mRNA mA modification in adult hippocampal neurogenesis remain...
2.
Li Q, Liu H, Li L, Guo H, Xie Z, Kong X, et al.
Cell Biosci
. 2023 Oct;
13(1):183.
PMID: 37779199
Background: N-methylguanosine (mG) is one of the most conserved modifications in nucleosides impacting mRNA export, splicing, and translation. However, the precise function and molecular mechanism of internal mRNA mG methylation...
3.
Liao W, Luo H, Ruan Y, Mai Y, Liu C, Chen J, et al.
Front Neurosci
. 2023 Jan;
16:1060111.
PMID: 36605552
Background And Objective: Alzheimer's disease (AD) is the most common type of dementia, with its pathology like beta-amyloid and phosphorylated tau beginning several years before the clinical onset. The aim...
4.
Li Q, Wang X, Wang Z, Lin Z, Yang J, Chen J, et al.
Hum Vaccin Immunother
. 2022 Sep;
18(6):2121568.
PMID: 36113067
Bacillus Calmette - Guerin (BCG) is an immune regulator that can enhance hippocampal synaptic plasticity in rats; however, it is unclear whether it can improve synaptic function in a mouse...
5.
Xu B, Li Q, Wu Y, Wang H, Xu J, Liu H, et al.
FASEB J
. 2022 Jun;
36(7):e22392.
PMID: 35716070
N -methyladenosine (m A) is the most abundant mRNA modification affecting diverse biological processes. However, the functions and precise mechanisms of m A signaling in adult hippocampal neurogenesis and neurogenesis-related...
6.
Zhang L, Li Q, Wang H, Wu Y, Ye X, Gong Z, et al.
Stem Cells
. 2022 May;
40(1):59-73.
PMID: 35511865
Increased neurogenesis elicits antidepressive-like effects. The antidiabetic drug metformin (Met) reportedly promotes hippocampal neurogenesis, which ameliorates spatial memory deficits and depression-like behaviors. However, the precise molecular mechanisms underpinning Met-induced neuronal...
7.
Ye X, Wu Y, Xu J, Liu H, Wang H, Li Q, et al.
Pharmacol Res
. 2022 Apr;
179:106235.
PMID: 35472635
Adult hippocampal neurogenesis (AHN) is heavily implicated in the pathogenesis of various neuropsychiatric disorders. The mangiferin (MGF), a bioactive compound of the mango, reportedly produces biological effects on a variety...
8.
Li Q, Wu Y, Chen J, Xuan A, Wang X
Acta Neurol Scand
. 2021 Nov;
145(3):273-278.
PMID: 34779509
Microglia are a type of glial cells that play a key role in the repair of damage to the central nervous system (CNS). In the pathological condition of Alzheimer's disease...
9.
Wang J, Huang J, Li Y, Yao S, Wu C, Wang Y, et al.
Cell Biosci
. 2021 Feb;
11(1):29.
PMID: 33536056
Background: The ketogenic diet (KD) has been recognized as a potentially effective therapy to treat neuropsychiatric diseases, including epilepsy. Previous studies have indicated that KD treatment elevates γ-Amino butyric acid...
10.
Zhang W, Gong J, Ding L, Zhang Z, Pan X, Chen X, et al.
Cell Death Dis
. 2020 Oct;
11(10):897.
PMID: 33093440
Parkinson's disease (PD) is a common neurodegenerative disease characterized by Lewy body formation and progressive dopaminergic neuron death in the substantia nigra (SN). Genetic susceptibility is a strong risk factor...