Xu Shi-Wen
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Explore the profile of Xu Shi-Wen including associated specialties, affiliations and a list of published articles.
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Articles
52
Citations
2065
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Recent Articles
1.
Quesnel K, Shi-Wen X, Hutchenreuther J, Xiao Y, Liu S, Peidl A, et al.
Matrix Biol Plus
. 2021 Feb;
3:100009.
PMID: 33543008
The microenvironment contributes to the excessive connective tissue deposition that characterizes fibrosis. Members of the CCN family of matricellular proteins are secreted by fibroblasts into the fibrotic microenvironment; however, the...
2.
Shi-Wen X, Racanelli M, Ali A, Simon A, Quesnel K, Stratton R, et al.
J Cell Commun Signal
. 2021 Jan;
15(1):71-80.
PMID: 33398723
Fibrosis is perpetuated by an autocrine, pro-adhesive signaling loop maintained by the synthetic and contractile abilities of myofibroblasts and the stiff, highly-crosslinked extracellular matrix. Transcriptional complexes that are exquisitely responsive...
3.
Murphy-Marshman H, Quensel K, Shi-Wen X, Barnfield R, Kelly J, Peidl A, et al.
PLoS One
. 2017 Oct;
12(10):e0186740.
PMID: 29049376
TGFbeta induces fibrogenic responses in fibroblasts. Reactive oxygen species (ROS)/nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) may contribute to fibrogenic responses. Here, we examine if the antioxidant N-acetylcysteine (NAC), the...
4.
Ikeda T, Fragiadaki M, Shi-Wen X, Ponticos M, Khan K, Denton C, et al.
Biochem Biophys Rep
. 2017 Sep;
7:246-252.
PMID: 28955913
In the enhancer region of the human type I collagen alpha 2 () gene, we identified cis-elements for the transcription factor CUX1. However, the role of CUX1 in fibrosis remains...
5.
Ikeda T, Fragiadaki M, Shi-Wen X, Ponticos M, Khan K, Denton C, et al.
Data Brief
. 2016 Sep;
8:1377-80.
PMID: 27583344
This data article contains complementary figures related to the research article entitled, "Transforming growth factor-β-induced CUX1 isoforms are associated with fibrosis in systemic sclerosis lung fibroblasts" (Ikeda et al. (2016)...
6.
Chen Y, Leask A, Abraham D, Kennedy L, Shi-Wen X, Denton C, et al.
Fibrogenesis Tissue Repair
. 2015 Mar;
8:4.
PMID: 25774218
[This corrects the article DOI: 10.1186/1755-1536-4-9.].
7.
Lindahl G, Stock C, Shi-Wen X, Leoni P, Sestini P, Howat S, et al.
Respir Res
. 2013 Aug;
14:80.
PMID: 23915349
Background: Interstitial lung disease is a major cause of morbidity and mortality in systemic sclerosis (SSc), with insufficiently effective treatment options. Progression of pulmonary fibrosis involves expanding populations of fibroblasts,...
8.
Shi-Wen X, Thompson K, Khan K, Liu S, Murphy-Marshman H, Baron M, et al.
Rheumatology (Oxford)
. 2012 Sep;
51(12):2146-54.
PMID: 22977060
Objective: Fibrotic diseases such as SSc (systemic sclerosis, scleroderma) are characterized by the abnormal presence of the myofibroblast, a specialized type of fibroblast that overexpresses the highly contractile protein α-smooth...
9.
Thoua N, Derrett-Smith E, Khan K, Dooley A, Shi-Wen X, Denton C
Rheumatology (Oxford)
. 2012 Aug;
51(11):1989-98.
PMID: 22908328
Objective: Gastrointestinal involvement occurs in up to 90% of patients with SSc. Animal models of SSc mimic some of the pathophysiological disease processes of SSc. The transgenic (TG) mouse strain...
10.
Dreifaldt M, Souza D, Bodin L, Shi-Wen X, Dooley A, Muddle J, et al.
Angiology
. 2012 May;
64(4):293-9.
PMID: 22569406
No-touch (NT) saphenous vein (SV) grafts are superior to SVs harvested by the conventional technique (CT), with a patency comparable with the internal thoracic artery (ITA). Preservation of the vasa...