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Mark Eastwood

Explore the profile of Mark Eastwood including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 846
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Recent Articles
1.
Zuhair R, Eastwood M, Jones M, Cross A, Hester J, Issa F, et al.
bioRxiv . 2024 Jan; PMID: 38234756
Evaluating the contribution of the tumour microenvironment (TME) in tumour progression has proven a complex challenge due to the intricate interactions within the TME. Multiplexed imaging is an emerging technology...
2.
Zamanitajeddin N, Jahanifar M, Bilal M, Eastwood M, Rajpoot N
Med Image Anal . 2024 Jan; 93:103071. PMID: 38199068
Colorectal cancer (CRC) is a primary global health concern, and identifying the molecular pathways, genetic subtypes, and mutations associated with CRC is crucial for precision medicine. However, traditional measurement techniques...
3.
Dawood M, Eastwood M, Jahanifar M, Young L, Ben-Hur A, Branson K, et al.
Cell Rep Med . 2023 Dec; 4(12):101313. PMID: 38118424
Identification of the gene expression state of a cancer patient from routine pathology imaging and characterization of its phenotypic effects have significant clinical and therapeutic implications. However, prediction of expression...
4.
Eastwood M, Sailem H, Marc S, Gao X, Offman J, Karteris E, et al.
Cell Rep Med . 2023 Oct; 4(10):101226. PMID: 37816348
Mesothelioma is classified into three histological subtypes, epithelioid, sarcomatoid, and biphasic, according to the relative proportions of epithelioid and sarcomatoid tumor cells present. Current guidelines recommend that the sarcomatoid component...
5.
Eastwood M, Marc S, Gao X, Sailem H, Offman J, Karteris E, et al.
Artif Intell Med . 2023 Sep; 143:102628. PMID: 37673586
Malignant Mesothelioma is a difficult to diagnose and highly lethal cancer usually associated with asbestos exposure. It can be broadly classified into three subtypes: Epithelioid, Sarcomatoid, and a hybrid Biphasic...
6.
Bilal M, Jewsbury R, Wang R, AlGhamdi H, Asif A, Eastwood M, et al.
Med Image Anal . 2023 Jul; 88:102885. PMID: 37423055
Image analysis and machine learning algorithms operating on multi-gigapixel whole-slide images (WSIs) often process a large number of tiles (sub-images) and require aggregating predictions from the tiles in order to...
7.
Graham S, Minhas F, Bilal M, Ali M, Tsang Y, Eastwood M, et al.
Gut . 2023 May; 72(9):1709-1721. PMID: 37173125
Objective: To develop an interpretable artificial intelligence algorithm to rule out normal large bowel endoscopic biopsies, saving pathologist resources and helping with early diagnosis. Design: A graph neural network was...
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Elliott C, Wang J, Guo X, Xu S, Eastwood M, Guan J, et al.
J Cell Sci . 2012 Jan; 125(Pt 1):121-32. PMID: 22266908
The matricellular protein periostin is expressed in the skin. Although periostin has been hypothesized to contribute to dermal homeostasis and repair, this has not been directly tested. To assess the...
10.
Chen Y, Leask A, Abraham D, Kennedy L, Shi-Wen X, Denton C, et al.
Fibrogenesis Tissue Repair . 2011 Apr; 4(1):9. PMID: 21453480
Background: The mechanism underlying the ability of fibroblasts to contract a collagen gel matrix is largely unknown. Fibroblasts from scarred (lesional) areas of patients with the fibrotic disease scleroderma show...