Xingxian Zhang
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Explore the profile of Xingxian Zhang including associated specialties, affiliations and a list of published articles.
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25
Citations
171
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Recent Articles
1.
Zhu X, Bao C, Zhang X, Chen N, Guan M, Liao Y, et al.
J Org Chem
. 2024 Dec;
90(1):768-776.
PMID: 39723958
In this work, a switchable synthesis of β-ketosulfone and α-chloroketone through a radical difunctionalization of alkenes is reported. The transformation works well under iron peroxo species/photoredox dual catalysis and an...
2.
Shen C, Mao Z, Chen T, Wei Y, Zhou T, Zhong N, et al.
J Med Chem
. 2024 Dec;
68(1):361-386.
PMID: 39699557
Acute lung injury (ALI) is a disease characterized by pulmonary inflammation, blood barrier functional disorder, and hypoxemia. Herein, a series of 2-aminopyrimidine derivatives were synthesized. Most of them exhibited inhibitory...
3.
Luo F, Wang W, Xiang C, Zeng L, Zhang C, Zhang J, et al.
Org Lett
. 2024 Nov;
26(48):10224-10228.
PMID: 39576220
A novel annulation reaction of prop-2-ynylsulfonium salts with sulfur ylides and nitrosobenzenes has been developed, affording various benzazepines in moderate to good yields. Prop-2-ynylsulfonium salts act as C synthons in...
4.
Yang S, Chen K, Yu J, Jin Z, Li Z, Yu Y, et al.
iScience
. 2024 Nov;
27(11):111024.
PMID: 39559762
Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a severe inflammatory condition that remains refractory; however, its molecular mechanisms are largely unknown. Previous studies have shown numerous compounds containing...
5.
Wang J, Li C, Shen C, Zhang Z, Liu M, Zhang X
J Org Chem
. 2024 Nov;
89(23):17321-17330.
PMID: 39520371
A Ru(II)-catalyzed migratory insertion of carbene into C-H bonds of 4-aryl-pyrrolo[2,3-]pyrimidines has been developed. This transformation endows the facile fabrication of C-C bonds with high atom economy, good regioselectivity, and...
6.
Tang J, Liu Y, Qiu B, Zhang Z, Zhang X
Org Lett
. 2024 Oct;
26(41):8708-8712.
PMID: 39373319
An efficient and practical system for metal-free catalytic chlorination of (hetero)arenes by using readily available and inexpensive TsCl and PhI(OAc) is described. This newly developed protocol has been achieved by...
7.
Ma S, Ma Q, Hu S, Mo X, Zhu C, Zhang X, et al.
Cell Rep
. 2024 Sep;
43(9):114717.
PMID: 39264811
Hyperfunction of the dopamine system has been implicated in manic episodes in bipolar disorders. How dopaminergic neuronal function is regulated in the pathogenesis of mania remains unclear. Histaminergic neurons project...
8.
Liu M, Qiu B, Zhang Z, Zheng Y, Yuan J, Li H, et al.
J Org Chem
. 2024 May;
89(11):8023-8034.
PMID: 38768046
Herein, we report the Pd(II)-catalyzed direct C-H arylation of pyrrolo[2,3-]pyrimidine derivatives with aryl iodides, which is enabled by bidentate pyridine-pyridine ligands. A range of aryl iodides proved to be suitable...
9.
Sun K, Sun T, Jiang Y, Shi J, Sun W, Zheng Y, et al.
Chem Commun (Camb)
. 2024 May;
60(44):5755-5758.
PMID: 38747147
Here, we describe an iron-catalyzed benzylic C-H thiolation of alkylarenes photoinduced ligand-to-metal charge-transfer. The protocol features operational simplicity, mild reaction conditions, and the use of FeCl as catalyst and thiols/disulfides...
10.
Zhang Z, Liu M, Liu M, Pan C, Mao Z, Zhang X
J Org Chem
. 2024 Feb;
89(5):2996-3009.
PMID: 38359468
An efficient and highly regioselective C6-phosphorylation protocol for pyrrolo[2,3-]pyrimidine (7-DAP) derivatives with various H-phosphine oxides induced by visible light at room temperature is described for the first time. This protocol...