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Xin Sheng Zhao

Explore the profile of Xin Sheng Zhao including associated specialties, affiliations and a list of published articles. Areas
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Articles 42
Citations 404
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Recent Articles
1.
He S, Yang C, Peng S, Chen C, Zhao X
RSC Adv . 2022 May; 9(26):14745-14749. PMID: 35516350
We found that apo DNA methyltransferase M.HhaI under the physiological salt concentration does not possess the structure characterized by X-ray crystallography; instead, it interchanges between prefolded and unfolded states. Only...
2.
Pan S, Yang C, Zhao X
Sci Rep . 2020 Sep; 10(1):14871. PMID: 32913243
Outer membrane proteins (OMPs) are essential to gram-negative bacteria, and molecular chaperones prevent the OMPs from aggregation in the periplasm during the OMPs biogenesis. Skp is one of the molecular...
3.
Peng S, Wang X, Zhang L, He S, Zhao X, Huang X, et al.
Proc Natl Acad Sci U S A . 2020 Aug; 117(36):21889-21895. PMID: 32820079
DNA glycosylase is responsible for repairing DNA damage to maintain the genome stability and integrity. However, how glycosylase can efficiently and accurately recognize DNA lesions across the enormous DNA genome...
4.
Yang C, Peng S, Chen C, Zhao X
Biochem J . 2020 Jul; 477(16):2949-2965. PMID: 32729902
The biogenesis of outer membrane proteins (OMPs) is an extremely challenging process. In the periplasm of Escherichia coli, a group of quality control factors work together to exercise the safe-guard...
5.
Li G, He C, Bu P, Bi H, Pan S, Sun R, et al.
ACS Chem Biol . 2018 Mar; 13(4):1082-1089. PMID: 29543429
Skp and SurA are both periplasmic chaperones involved in the biogenesis of Escherichia coli β-barrel outer membrane proteins (OMPs). It is commonly assumed that SurA plays a major role whereas...
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7.
Meng L, He S, Zhao X
J Phys Chem B . 2017 Nov; 121(50):11262-11272. PMID: 29155588
Fluorescence correlation spectroscopy (FCS) encodes the information on the equilibrium constant (K), the relative fluorescence brightness of fluorophore (Q), and the forward and backward reaction rate constants (k and k)...
8.
Zhang J, Pan B, Li Z, Zhao X, Huang L
Sci Rep . 2017 Jul; 7(1):5494. PMID: 28710489
All cellular organisms encode type IA topoisomerases which catalyze DNA topological changes essential for DNA transactions. However, the kinetics of the reaction catalyzed by these enzymes remains poorly characterized. Here...
9.
Wu Z, Bi H, Pan S, Meng L, Zhao X
J Phys Chem B . 2016 Oct; 120(45):11674-11682. PMID: 27775360
Fluorescence correlation spectroscopy (FCS) is a powerful tool to investigate molecular diffusion and relaxations, which may be utilized to study many problems such as molecular size and aggregation, chemical reaction,...
10.
Bi H, Yin Y, Pan B, Li G, Zhao X
J Phys Chem Lett . 2016 May; 7(10):1865-71. PMID: 27140004
Single-molecule fluorescence measurements have been widely used to explore kinetics and dynamics of biological systems. Among them, single-molecule imaging (SMI) is good at tracking processes slower than tens of milliseconds,...