Xiaolong Tian
Overview
Explore the profile of Xiaolong Tian including associated specialties, affiliations and a list of published articles.
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Articles
51
Citations
1574
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Recent Articles
1.
Zhang F, Chow R, He E, Dong C, Xin S, Mirza D, et al.
Nat Biotechnol
. 2025 Feb;
PMID: 39901026
No abstract available.
2.
Multiplexed inhibition of immunosuppressive genes with Cas13d for combinatorial cancer immunotherapy
Zhang F, Chow R, He E, Dong C, Xin S, Mirza D, et al.
Nat Biotechnol
. 2025 Jan;
PMID: 39820813
The complex nature of the immunosuppressive tumor microenvironment (TME) requires multi-agent combinations for optimal immunotherapy. Here we describe multiplex universal combinatorial immunotherapy via gene silencing (MUCIG), which uses CRISPR-Cas13d to...
3.
Tian X, Fan R
Genomics Proteomics Bioinformatics
. 2024 Dec;
22(6).
PMID: 39724297
No abstract available.
4.
Baysoy A, Tian X, Zhang F, Renauer P, Bai Z, Shi H, et al.
bioRxiv
. 2024 Nov;
PMID: 39605490
Perturb-seq enabled the profiling of transcriptional effects of genetic perturbations in single cells but lacks the ability to examine the impact on tissue environments. We present Perturb-DBiT for simultaneous co-sequencing...
5.
Yang G, Yang S, Li J, Jiang P, Tian X, Wang X, et al.
Eur J Pharmacol
. 2024 Oct;
985:177058.
PMID: 39413949
Aims: Leukemia is hematopoietic stem cell malignant tumor with poor outcomes. Histone deacetylase 1 (HDAC1) is highly expressed in leukemia and current HDAC1 inhibitors have clinical limitations in leukemia therapy....
6.
Bai Z, Zhang D, Gao Y, Tao B, Zhang D, Bao S, et al.
Cell
. 2024 Oct;
187(23):6760-6779.e24.
PMID: 39353436
The capability to spatially explore RNA biology in formalin-fixed paraffin-embedded (FFPE) tissues holds transformative potential for histopathology research. Here, we present pathology-compatible deterministic barcoding in tissue (Patho-DBiT) by combining in...
7.
Yu J, Long B, Li Z, Tian X, Li D, Long J, et al.
Cardiovasc Res
. 2024 Jun;
120(12):1442-1455.
PMID: 38850163
Aims: The widespread use of immune checkpoint inhibitors (ICIs) has demonstrated significant survival benefits for cancer patients and also carries the risk of immune-related adverse events. ICI-associated myocarditis is a...
8.
Yin D, Zhong Y, Ling S, Lu S, Wang X, Jiang Z, et al.
Nat Biomed Eng
. 2024 May;
9(2):185-200.
PMID: 38714892
Messenger RNA vaccines lack specificity for dendritic cells (DCs)-the most effective cells at antigen presentation. Here we report the design and performance of a DC-targeting virus-like particle pseudotyped with an...
9.
Liang M, Wang L, Tian X, Wang K, Zhu X, Huang L, et al.
Ann Rheum Dis
. 2024 Apr;
83(9):1144-1155.
PMID: 38684324
Objectives: In the complex panorama of autoimmune diseases, the characterisation of pivotal contributing autoantibodies that are involved in disease progression remains challenging. This study aimed to employ a global antibody...
10.
Bai Z, Zhang D, Gao Y, Tao B, Bao S, Enninful A, et al.
bioRxiv
. 2024 Feb;
PMID: 38370833
Spatial transcriptomics has emerged as a powerful tool for dissecting spatial cellular heterogeneity but as of today is largely limited to gene expression analysis. Yet, the life of RNA molecules...