Xiaohong Huo
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Explore the profile of Xiaohong Huo including associated specialties, affiliations and a list of published articles.
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33
Citations
343
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Recent Articles
1.
Yu G, Wang X, Luo Y, Li G, Ding R, Shi R, et al.
J Chem Inf Model
. 2025 Jan;
65(1):312-325.
PMID: 39744764
Despite remarkable advancements in the organic synthesis field facilitated by the use of machine learning (ML) techniques, the prediction of reaction outcomes, including yield estimation, catalyst optimization, and mechanism identification,...
2.
Li P, Zhang Y, Liu Z, Kong Q, Fu L, Huo X
Org Lett
. 2024 Nov;
26(48):10356-10363.
PMID: 39568192
A Pd-catalyzed asymmetric Heck cascade reaction involving the intramolecular carbopalladation of unsaturated hydrocarbons, followed by nucleophilic trapping of the resulting palladium species, is a powerful approach for constructing chiral -heterocycles....
3.
Li P, Zheng E, Li G, Luo Y, Huo X, Ma S, et al.
Science
. 2024 Aug;
385(6712):972-979.
PMID: 39208090
The precise control of and configurations of the carbon-carbon double bond in alkene synthesis has long been a fundamental challenge in synthetic chemistry, even more pronounced when simultaneously striving to...
4.
Zhu W, Han C, Yang G, Huo X, Zhang W
J Am Chem Soc
. 2024 Aug;
146(38):26121-26130.
PMID: 39099165
The Wacker and Wacker-type reactions are some of the most fundamental and powerful transformations in organic chemistry for their ability to efficiently produce valuable chemicals. Remarkable progress has been achieved...
5.
Li P, Liu Z, Huo X, Zhang W
Angew Chem Int Ed Engl
. 2024 May;
63(35):e202407498.
PMID: 38752892
The construction of chiral motifs containing nonadjacent stereocenters in an enantio- and diastereoselective manner has long been a challenging task in synthetic chemistry, especially with respect to their stereodivergent synthesis....
6.
Zhang J, Luo Y, Zheng E, Huo X, Ma S, Zhang W
J Am Chem Soc
. 2024 Mar;
146(13):9241-9251.
PMID: 38502927
Much attention has been focused on the catalytic asymmetric creation of single chiral centers or two adjacent stereocenters. However, the asymmetric construction of two nonadjacent stereocenters is of significant importance...
7.
Shi R, Yu G, Huo X, Yang Y
J Cheminform
. 2024 Feb;
16(1):22.
PMID: 38403627
Developing machine learning models with high generalization capability for predicting chemical reaction yields is of significant interest and importance. The efficacy of such models depends heavily on the representation of...
8.
Yao J, Shao L, Kang X, Zhu M, Huo X, Wang X
J Org Chem
. 2024 Jan;
89(3):1719-1726.
PMID: 38204281
As an interim paradigm for the catalysts between those based on more conventional mononuclear molecular Pd complexes and Pd nanoparticles widely used in organic synthesis, polynuclear palladium clusters have attracted...
9.
Luo Y, Ma Y, Li G, Huo X, Zhang W
Angew Chem Int Ed Engl
. 2023 Oct;
62(47):e202313838.
PMID: 37815160
Fluorinated amino acids and related peptides/proteins have been found widespread applications in pharmaceutical and agricultural compounds. However, strategies for introducing a C-F bond into amino acids in an enantioselective manner...
10.
Zhao L, Luo Y, Xiao J, Huo X, Ma S, Zhang W
Angew Chem Int Ed Engl
. 2023 Jan;
62(9):e202218146.
PMID: 36594710
The stereodivergent synthesis of allene compounds bearing α,β-adjacent central chiralities has been realized via the Pd/Cu-catalyzed dynamic kinetic asymmetric alkylation of racemic allenylic esters. The matched reactivity of bimetallic catalytic...