Xiaobao Ding
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Explore the profile of Xiaobao Ding including associated specialties, affiliations and a list of published articles.
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10
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64
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Recent Articles
1.
Ding X, Zhang L, Fan M, Li L
NPJ Syst Biol Appl
. 2025 Jan;
11(1):4.
PMID: 39788975
Breast cancer prognosis is complicated by tumor heterogeneity. Traditional methods focus on cancer-specific gene signatures, but cross-cancer strategies that provide deeper insights into tumor homogeneity are rarely used. Immunotherapy, particularly...
2.
Ding X, Wang G, Lin Y, Hu W, Chen C, Gao J, et al.
Cell Biol Toxicol
. 2025 Jan;
41(1):24.
PMID: 39779529
Neuropathic pain is a type of pain caused by an injury or disease of the somatosensory nervous system. Currently, there is still absence of effective therapeutic drugs for neuropathic pain,...
3.
Ding X, Zhang L, Fan M, Li L
Brief Bioinform
. 2024 Aug;
25(5).
PMID: 39167797
Immunotherapy with immune checkpoint inhibitors (ICIs) is increasingly used to treat various tumor types. Determining patient responses to ICIs presents a significant clinical challenge. Although components of the tumor microenvironment...
4.
Zhang Y, Ding X, Guo L, Zhong Y, Xie J, Xu Y, et al.
STAR Protoc
. 2024 Feb;
5(1):102881.
PMID: 38386546
Here, we present a protocol for inducing fibrosis in human kidney-2 (HK2) cells followed by quantitative real-time PCR analysis of fibrosis-related genes. We describe steps for growing and expanding cells,...
5.
Zhang Y, Ding X, Guo L, Zhong Y, Xie J, Xu Y, et al.
iScience
. 2023 Nov;
26(11):107332.
PMID: 37927553
Chronic kidney disease (CKD) is a common disease that seriously endangers human health. However, the potential relationship between xanthine oxidoreductase (XOR) activity and CKD remains unclear. In this study, we...
6.
Ding X, Lin Y, Chen C, Yan B, Liu Q, Zheng H, et al.
Biol Psychiatry
. 2023 Mar;
94(8):672-684.
PMID: 37001844
Background: Chronic pain can induce depressive emotion. DNA methyltransferases (DNMTs) have been shown to be involved in the development of chronic pain and depression. However, the role and mechanism of...
7.
Ding X, Lin Y, Yan B, Jiao X, Liu Q, Miao H, et al.
J Pain
. 2022 Oct;
24(3):449-462.
PMID: 36257574
Chronic pain is frequently comorbid with depression. However, the mechanisms underlying chronic pain-induced depression remain unclear. Here, we found that DNA methyltransferase 1 (DNMT1) was upregulated in the central amygdala...
8.
Yan B, Liu Q, Ding X, Lin Y, Jiao X, Wu Y, et al.
Oxid Med Cell Longev
. 2022 Sep;
2022:4722647.
PMID: 36092157
Numerous studies have shown that mitochondrial dysfunction manifested by increased mitochondrial permeability transition pore (mPTP) opening and reactive oxygen species (ROS) level, and decreased mitochondrial membrane potential (MMP) plays an...
9.
Jiao X, Wang R, Ding X, Yan B, Lin Y, Liu Q, et al.
Front Mol Neurosci
. 2022 Aug;
15:920216.
PMID: 35959106
Long-term chronic pain can lead to depression. However, the mechanism underlying chronic pain-related depression remains unclear. Sirtuin 1 (SIRT1) is a nicotinamide adenine dinucleotide (NAD)-dependent histone deacetylase (HDAC). Our previous...
10.
Shi N, Lin Y, Yan B, Jiao X, Ding X, Wu Y, et al.
Eur J Pharmacol
. 2021 Dec;
914:174666.
PMID: 34861210
Diabetes mellitus (DM) is associated with accelerated cognitive decline. However, the mechanism of diabetic cognitive impairment remains poorly understood. In this study, we found that the expression of Sirtuin 1...