Xiao-yi Qi
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Explore the profile of Xiao-yi Qi including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
150
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Recent Articles
1.
Liang S, Ge G, Xia Y, Qi X, Wang A, Tu C, et al.
Yao Xue Xue Bao
. 2018 Jul;
52(2):291-5.
PMID: 29979523
Daphnetin is quickly eliminated in rats after dosing, but the mechanism remains unclear. This
study was aimed to investigate the in vitro metabolism of daphnetin using rat liver S9 fractions...
2.
Liang S, Ge G, Xia Y, Pei-Pei D, Ping W, Qi X, et al.
Xenobiotica
. 2016 Jul;
47(6):498-504.
PMID: 27435571
1. Finding and developing inhibitors of catechol-O-methyltransferase (COMT) from natural products is highly recommended. Daphnetin, a naturally occurring catechol from the family thymelaeaceae, has a chemical structure similar to several...
3.
Xin H, Qi X, Wu J, Wang X, Li Y, Hong J, et al.
Food Chem Toxicol
. 2016 Feb;
90:112-22.
PMID: 26875642
Licochalcone A (LCA) is a major bioactive compound in Licorice, a widely used herbal medicine. In this study, the inhibitory effects of LCA against human UDP-glucuronosyltransferases (UGTs) and LCA associated...
4.
Liang S, Xia Y, Hou J, Ge G, Zhang J, He Y, et al.
J Pharm Sci
. 2016 Feb;
105(2):808-816.
PMID: 26869431
Our previous study demonstrated that daphnetin is subject to glucuronidation in vitro. However, daphnetin metabolism is still poorly documented. This study aimed to investigate daphnetin metabolism and its consequent effect...
5.
Liang S, Ge G, Xia Y, Zhang J, Qi X, Tu C, et al.
J Pharm Sci
. 2015 Jun;
104(10):3557-64.
PMID: 26104686
The C-8 phenol group is essential to exert the bioactivities of daphnetin, but it is readily conjugated with glucuronic acid prior to excretion. In this study, daphnetin-7-methylether (7M-DNP) was used...
6.
Jiang L, Liang S, Wang C, Ge G, Huo X, Qi X, et al.
Sci Rep
. 2015 Apr;
5:9627.
PMID: 25884245
Glucuronidation mediated by uridine 5'-diphospho (UDP)-glucuronosyltransferase is an important detoxification pathway. However, identifying a selective probe of UDP- glucuronosyltransferase is complicated because of the significant overlapping substrate specificity displayed by...
7.
Lin M, Zhang B, Shen N, Dong X, Zhang C, Qi X, et al.
Eur J Dermatol
. 2014 Oct;
24(6):676-82.
PMID: 25335433
Background: Recent studies have shown that vitiligo is a T-cell mediated autoimmune disease. Skin-homing cytotoxic T lymphocytes expressing cutaneous lymphocyte-associated antigen (CLA) have been suggested to be responsible for the...
8.
Wang A, Qi X
IUBMB Life
. 2013 Jul;
65(9):748-58.
PMID: 23893853
The RAS/RAF/MEK/ERK pathway has been reported to be activated in over 80% of all cutaneous melanomas, making it the focus of many scientific studies in the melanoma field. Discoveries of...
9.
Zhang B, Lin M, Qi X, Zhang R, Wei Z, Zhu J, et al.
Eur J Dermatol
. 2013 Jun;
23(3):331-8.
PMID: 23782916
Background: Vitiligo is caused by melanocyte depletion. Studies have suggested that skin-homing cytotoxic T lymphocytes that express cutaneous lymphocyte-associated antigen (CLA) are responsible for melanocyte depletion. The characteristics of these...
10.
Qi X, Liang S, Ge G, Liu Y, Dong P, Zhang J, et al.
Food Chem Toxicol
. 2013 Mar;
56:392-7.
PMID: 23500771
Sanguinarine (SAG) has been recognized as an anticancer drug candidate. However, the drug-drug interactions (DDI) potential for SAG via the inhibition against human cytochrome P450 (CYP) enzymes remains unclear. In...