Xiao-Wei Chen
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Explore the profile of Xiao-Wei Chen including associated specialties, affiliations and a list of published articles.
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Articles
203
Citations
2721
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Recent Articles
1.
Liver ALKBH5 regulates glucose and lipid homeostasis independently through GCGR and mTORC1 signaling
Ding K, Zhang Z, Han Z, Shi L, Li X, Liu Y, et al.
Science
. 2025 Feb;
387(6737):eadp4120.
PMID: 40014709
Maintaining glucose and lipid homeostasis is crucial for health, with dysregulation leading to metabolic diseases such as type 2 diabetes mellitus (T2DM) and metabolic dysfunction-associated fatty liver disease (MAFLD). This...
2.
Chen X, Don A, Fedorova M, Harayama T, Krahmer N, Nagata S, et al.
Nat Cell Biol
. 2025 Feb;
27(2):169-174.
PMID: 39910286
No abstract available.
3.
Wang Y, Feng X, Zhou W, Huang R, Hu Y, Hui H, et al.
Life Metab
. 2025 Jan;
2(6):load040.
PMID: 39872857
Precise control of circulating lipid levels is vital in both health and disease. We recently uncovered that bulk lipids, transported by lipoproteins, enter the circulation initially via the coat protein...
4.
Yu Z, Liu J, Liu Z, Liu X, Tuo J, Li J, et al.
Alzheimers Dement
. 2024 Dec;
21(2):e14402.
PMID: 39740209
Introduction: The triggering receptor expressed on myeloid cells 2 (TREM2) arginine-47-histidine (R47H) mutation is a significant risk for Alzheimer's disease (AD) with unclear mechanisms. Previous studies focused on microglial amyloid-β...
5.
Mu C, Liu P, Liu L, Wang Y, Liu K, Li X, et al.
Proc Natl Acad Sci U S A
. 2024 Nov;
121(48):e2400464121.
PMID: 39565307
KCTD10, a member of the potassium channel tetramerization domain (KCTD) family, is implicated in neuropsychiatric disorders and functions as a substrate recognition component within the RING-type ubiquitin ligase complex. A...
6.
Wang Y, Chen X, Zhu M, Zhou X, Sun S, Du Z, et al.
Int J Biol Macromol
. 2024 Nov;
283(Pt 2):137416.
PMID: 39532168
Plant-based diets are currently gaining more popularity as a means of reducing the environmental footprint and promoting human health. Herein, plant protein-based acidic high internal phase emulsion gels (HIPE gels)...
7.
Li D, Zhang X, Yao Y, Sun X, Sun J, Ma X, et al.
Proc Natl Acad Sci U S A
. 2024 Oct;
121(44):e2412653121.
PMID: 39441632
EfpA, the first major facilitator superfamily (MFS) protein identified in (Mtb), is an essential efflux pump implicated in resistance to multiple drugs. EfpA-inhibitors have been developed to kill drug-tolerant Mtb....
8.
Bai G, Zhao M, Chen X, Ma C, Ma Y, Xianqing H
J Sci Food Agric
. 2024 Oct;
105(3):1737-1744.
PMID: 39390660
Background: Sea buckthorn (Hippophae rhamnoides L.) pulp oil is rich in functional components; however, low water solubility and stability limit its applications. This study fabricated sea buckthorn pulp oil microcapsules...
9.
Zhang L, Wang X, Chen X
Trends Endocrinol Metab
. 2024 Aug;
36(3):262-277.
PMID: 39164120
Triglyceride-rich lipoproteins (TRLs) play essential roles in human health and disease by transporting bulk lipids into the circulation. This review summarizes the fundamental mechanisms and diverse factors governing lipoprotein production,...
10.
Xiong X, Pan X, Luo X, Wang Y, Zhang X, Yang S, et al.
Theranostics
. 2024 Aug;
14(11):4297-4317.
PMID: 39113798
Although lactate supplementation at the reperfusion stage of ischemic stroke has been shown to offer neuroprotection, whether the role of accumulated lactate at the ischemia phase is neuroprotection or not...