Xavier Prasanna
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Explore the profile of Xavier Prasanna including associated specialties, affiliations and a list of published articles.
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17
Citations
306
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Recent Articles
1.
Li C, Sun X, Funcke J, Vanharanta L, Joffin N, Li Y, et al.
bioRxiv
. 2024 Aug;
PMID: 39211078
Adipogenin (Adig) is an evolutionarily conserved microprotein and is highly expressed in adipose tissues and testis. Here, we identify Adig as a critical regulator for lipid droplet formation in adipocytes....
2.
Wang L, Yang Z, Satoshi F, Prasanna X, Yan Z, Vihinen H, et al.
Nat Commun
. 2024 Jul;
15(1):6209.
PMID: 39043703
The Bin/Amphiphysin/Rvs (BAR) domain protein FAM92A1 is a multifunctional protein engaged in regulating mitochondrial ultrastructure and ciliogenesis, but its physiological role in the brain remains unclear. Here, we show that...
3.
Dumesnil C, Vanharanta L, Prasanna X, Omrane M, Carpentier M, Bhapkar A, et al.
Nat Commun
. 2023 Feb;
14(1):915.
PMID: 36807572
Cellular cholesterol can be metabolized to its fatty acid esters, cholesteryl esters (CEs), to be stored in lipid droplets (LDs). With triacylglycerols (TGs), CEs represent the main neutral lipids in...
4.
Prasanna X, Salo V, Li S, Ven K, Vihinen H, Jokitalo E, et al.
PLoS Biol
. 2021 Jan;
19(1):e3000998.
PMID: 33481779
Seipin is a disk-like oligomeric endoplasmic reticulum (ER) protein important for lipid droplet (LD) biogenesis and triacylglycerol (TAG) delivery to growing LDs. Here we show through biomolecular simulations bridged to...
5.
Prasanna X, Mohole M, Chattopadhyay A, Sengupta D
Chem Phys Lipids
. 2019 Dec;
227:104852.
PMID: 31866438
G protein-coupled receptors (GPCRs) are transmembrane receptors that mediate a large number of cellular responses. The organization of GPCRs into dimers and higher-order oligomers is known to allow a larger...
6.
Li S, Prasanna X, Salo V, Vattulainen I, Ikonen E
Nat Methods
. 2019 Oct;
16(11):1193.
PMID: 31636461
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
7.
Li S, Prasanna X, Salo V, Vattulainen I, Ikonen E
Nat Methods
. 2019 Aug;
16(9):866-869.
PMID: 31451765
Auxin-inducible degron technology allows rapid and controlled protein depletion. However, basal degradation without auxin and inefficient auxin-inducible depletion have limited its utility. We have identified a potent auxin-inducible degron system...
8.
Mohole M, Prasanna X, Sengupta D, Chattopadhyay A
Adv Exp Med Biol
. 2019 Jan;
1112:151-160.
PMID: 30637696
The interaction of G protein-coupled receptors (GPCRs) with cholesterol is a hallmark of their function, organization, and structural dynamics. Several cholesterol interaction sites, such as the cholesterol recognition amino acid...
9.
Sengupta D, Prasanna X, Mohole M, Chattopadhyay A
J Phys Chem B
. 2018 Apr;
122(22):5727-5737.
PMID: 29685028
Gprotein-coupled receptors (GPCRs) are seven transmembrane receptors that mediate a large number of cellular responses and are important drug targets. One of the current challenges in GPCR biology is to...
10.
Dubey V, Prasanna X, Sengupta D
J Phys Chem B
. 2017 Feb;
121(9):2111-2120.
PMID: 28186760
The insertion and association of membrane proteins is critical in several cellular processes. These processes were thought to be protein-driven, but increasing evidence points toward an important role of the...