Ilpo Vattulainen
Overview
Explore the profile of Ilpo Vattulainen including associated specialties, affiliations and a list of published articles.
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234
Citations
6213
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Recent Articles
1.
Korolainen H, Olzynska A, Pajerski W, Chytrosz-Wrobel P, Vattulainen I, Kulig W, et al.
Sci Rep
. 2024 Oct;
14(1):23805.
PMID: 39394419
Additives in vaping products, such as flavors, preservatives, or thickening agents, are commonly used to enhance user experience. Among these, Vitamin E acetate (VEA) was initially thought to be harmless...
2.
Lilja J, Kaivola J, Conway J, Vuorio J, Parkkola H, Roivas P, et al.
Nat Commun
. 2024 Sep;
15(1):8002.
PMID: 39266533
The KRAS oncogene drives many common and highly fatal malignancies. These include pancreatic, lung, and colorectal cancer, where various activating KRAS mutations have made the development of KRAS inhibitors difficult....
3.
Li C, Sun X, Funcke J, Vanharanta L, Joffin N, Li Y, et al.
bioRxiv
. 2024 Aug;
PMID: 39211078
Adipogenin (Adig) is an evolutionarily conserved microprotein and is highly expressed in adipose tissues and testis. Here, we identify Adig as a critical regulator for lipid droplet formation in adipocytes....
4.
Korshunova K, Kiuru J, Liekkinen J, Enkavi G, Vattulainen I, Bruininks B
J Chem Theory Comput
. 2024 Aug;
20(17):7635-7645.
PMID: 39189419
Martini 3 is a widely used coarse-grained simulation method for large-scale biomolecular simulations. It can be combined with a Go̅ model to realistically describe higher-order protein structures while allowing the...
5.
Wang L, Yang Z, Satoshi F, Prasanna X, Yan Z, Vihinen H, et al.
Nat Commun
. 2024 Jul;
15(1):6209.
PMID: 39043703
The Bin/Amphiphysin/Rvs (BAR) domain protein FAM92A1 is a multifunctional protein engaged in regulating mitochondrial ultrastructure and ciliogenesis, but its physiological role in the brain remains unclear. Here, we show that...
6.
Abraham B, Haikarainen T, Vuorio J, Girych M, Virtanen A, Kurttila A, et al.
Sci Adv
. 2024 Mar;
10(10):eadl2097.
PMID: 38457493
Janus kinase 2 (JAK2) mediates type I/II cytokine receptor signaling, but JAK2 is also activated by somatic mutations that cause hematological malignancies by mechanisms that are still incompletely understood. Quantitative...
7.
Enkavi G, Girych M, Moliner R, Vattulainen I, Castren E
Trends Biochem Sci
. 2024 Mar;
49(5):445-456.
PMID: 38433044
TrkB (neuronal receptor tyrosine kinase-2, NTRK2) is the receptor for brain-derived neurotrophic factor (BDNF) and is a critical regulator of activity-dependent neuronal plasticity. The past few years have witnessed an...
8.
Lolicato F, Steringer J, Saleppico R, Beyer D, Fernandez-Sobaberas J, Unger S, et al.
Elife
. 2024 Jan;
12.
PMID: 38252473
Fibroblast growth factor 2 (FGF2) exits cells by direct translocation across the plasma membrane, a type I pathway of unconventional protein secretion. This process is initiated by phosphatidylinositol-4,5-bisphosphate (PI(4,5)P)-dependent formation...
9.
Martin A, Tempra C, Yu Y, Liekkinen J, Thakker R, Lee H, et al.
Environ Sci Technol
. 2024 Jan;
58(3):1495-1508.
PMID: 38186267
Over the past decade, there has been a significant rise in the use of vaping devices, particularly among adolescents, raising concerns for effects on respiratory health. Pressingly, many recent vaping-related...
10.
McDowell M, Heimes M, Enkavi G, Farkas A, Saar D, Wild K, et al.
Nat Commun
. 2023 Nov;
14(1):7355.
PMID: 37963916
The eukaryotic guided entry of tail-anchored proteins (GET) pathway mediates the biogenesis of tail-anchored (TA) membrane proteins at the endoplasmic reticulum. In the cytosol, the Get3 chaperone captures the TA...