X Pares
Overview
Explore the profile of X Pares including associated specialties, affiliations and a list of published articles.
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Articles
73
Citations
816
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Recent Articles
1.
Pares X, Farres J, Kedishvili N, Duester G
Cell Mol Life Sci
. 2008 Nov;
65(24):3936-49.
PMID: 19011747
Retinoic acid (RA), the most active retinoid, is synthesized in two steps from retinol. The first step, oxidation of retinol to retinaldehyde, is catalyzed by cytosolic alcohol dehydrogenases (ADHs) of...
2.
Fernandez M, Porte S, Crosas E, Barbera N, Farres J, Biosca J, et al.
Cell Mol Life Sci
. 2007 May;
64(11):1419-27.
PMID: 17497241
Zeta-crystallins constitute a family of proteins with NADPH:quinone reductase activity found initially in mammalian lenses but now known to be present in many other organisms and tissues. Few proteins from...
3.
Hellgren M, Stromberg P, Gallego O, Martras S, Farres J, Persson B, et al.
Cell Mol Life Sci
. 2007 Feb;
64(4):498-505.
PMID: 17279314
The metabolism of all-trans- and 9-cis-retinol/ retinaldehyde has been investigated with focus on the activities of human, mouse and rat alcohol dehydrogenase 2 (ADH2), an intriguing enzyme with apparently different...
4.
Fernandez M, Biosca J, Pares X
Cell Mol Life Sci
. 2003 Jun;
60(5):1013-8.
PMID: 12827289
S-nitrosoglutathione (GSNO) formation represents a mechanism for storage and transport of nitric oxide. Analysis of human liver and Saccharomyces cerevisiae extracts has revealed the presence of only one enzyme able...
5.
Martinez S, Vaglenova J, Sabria J, Martinez M, Farres J, Pares X
Eur J Biochem
. 2001 Oct;
268(19):5045-56.
PMID: 11589695
The localization of alcohol dehydrogenase (ADH) in brain regions would demonstrate active ethanol metabolism in brain during alcohol consumption, which would be a new basis to explain the effects of...
6.
Hirschberg D, Cederlund E, Crosas B, Jonsson A, Tryggvason S, Farres J, et al.
Cell Mol Life Sci
. 2001 Oct;
58(9):1323-6.
PMID: 11577987
A recent finding of a novel class of retinol-active alcohol dehydrogenase (ADH) in frog prompted analysis of this activity in other vertebrate forms. Surprisingly, yet another and still more unrelated...
7.
Crosas B, Pares X, Farres J
Chem Biol Interact
. 2001 Apr;
130-132(1-3):435-44.
PMID: 11306065
Class IV alcohol dehydrogenase shows a deletion at position 117 with respect to class I enzymes, which typically have a Gly residue. In class I structures, Gly117 is part of...
8.
Gonzalez E, Fernandez M, Larroy C, Pares X, Biosca J
Chem Biol Interact
. 2001 Apr;
130-132(1-3):425-34.
PMID: 11306064
Using a conserved sequence motif, a new gene (YAL060W) of the MDR family has been identified in Saccharomyces cerevisiae. The expressed protein was a stereoespecific (2R,3R)-2,3-butanediol dehydrogenase (BDH). The best...
9.
Crosas B, Cederlund E, Torres D, Jornvall H, Farres J, Pares X
J Biol Chem
. 2001 Mar;
276(22):19132-40.
PMID: 11278684
Enzymes of the short chain and medium chain dehydrogenase/reductase families have been demonstrated to participate in the oxidoreduction of ethanol and retinoids. Mammals and amphibians contain, in the upper digestive...
10.
Jornvall H, Hoog J, Persson B, Pares X
Pharmacology
. 2000 Sep;
61(3):184-91.
PMID: 10971204
Alcohol dehydrogenase (ADH) constitutes a complex enzyme system with different forms and extensive multiplicity. A combination of constant and variable properties regarding function, multiplicity and structure of ADH is highlighted...