Wuhong Pei
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Explore the profile of Wuhong Pei including associated specialties, affiliations and a list of published articles.
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32
Citations
1581
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Recent Articles
1.
Weinstein R, Bishop K, Broadbridge E, Yu K, Carrington B, Elkahloun A, et al.
Int J Mol Sci
. 2022 Sep;
23(18).
PMID: 36142581
ZRSR2 (zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2) is an essential splicing factor involved in 3' splice-site recognition as a component of both the major and minor...
2.
Suppressing STAT3 activity protects the endothelial barrier from VEGF-mediated vascular permeability
Wang L, Astone M, Alam S, Zhu Z, Pei W, Frank D, et al.
Dis Model Mech
. 2021 Sep;
14(11).
PMID: 34542605
Vascular permeability triggered by inflammation or ischemia promotes edema, exacerbates disease progression and impairs tissue recovery. Vascular endothelial growth factor (VEGF) is a potent inducer of vascular permeability. VEGF plays...
3.
Suppressing STAT3 activity protects the endothelial barrier from VEGF-mediated vascular permeability
Wang L, Astone M, Alam S, Zhu Z, Pei W, Frank D, et al.
bioRxiv
. 2020 Nov;
PMID: 33140053
Vascular permeability triggered by inflammation or ischemia promotes edema, exacerbates disease progression, and impairs tissue recovery. Vascular endothelial growth factor (VEGF) is a potent inducer of vascular permeability. VEGF plays...
4.
Beck D, Ferrada M, Sikora K, Ombrello A, Collins J, Pei W, et al.
N Engl J Med
. 2020 Oct;
383(27):2628-2638.
PMID: 33108101
Background: Adult-onset inflammatory syndromes often manifest with overlapping clinical features. Variants in ubiquitin-related genes, previously implicated in autoinflammatory disease, may define new disorders. Methods: We analyzed peripheral-blood exome sequence data...
5.
Pei W, Xu L, Chen Z, Slevin C, Pettie K, Wincovitch S, et al.
NPJ Regen Med
. 2020 Mar;
5:6.
PMID: 32218991
Spinal muscular atrophy (SMA) is the most common genetic disease in children. SMA is generally caused by mutations in the gene . The survival of motor neurons (SMN) complex consists...
6.
McElderry J, Carrington B, Bishop K, Kim E, Pei W, Chen Z, et al.
Hum Mol Genet
. 2019 Nov;
28(24):4173-4185.
PMID: 31691804
DHX15, a DEAH box containing RNA helicase, is a splicing factor required for the last step of splicing. Recent studies identified a recurrent mutational hotspot, R222G, in DHX15 in ∼ ...
7.
Pei W, Burgess S
Methods Mol Biol
. 2018 Oct;
1874:459-474.
PMID: 30353530
A major strength of zebrafish as a model organism is their rapid, in vitro development. The easy access to embryos compared to mammals, allows larval molecular and cellular composition to...
8.
Unal Eroglu A, Mulligan T, Zhang L, White D, Sengupta S, Nie C, et al.
Front Cell Dev Biol
. 2018 Sep;
6:88.
PMID: 30186835
Thousands of genes have been implicated in retinal regeneration, but only a few have been shown to impact the regenerative capacity of Müller glia-an adult retinal stem cell with untapped...
9.
Tseng W, Loeb H, Pei W, Tsai-Morris C, Xu L, Cluzeau C, et al.
Dis Model Mech
. 2018 Aug;
11(9).
PMID: 30135069
Niemann-Pick disease type C1 (NPC1) is a rare autosomal recessive lysosomal storage disease primarily caused by mutations in NPC1 is characterized by abnormal accumulation of unesterified cholesterol and glycolipids in...
10.
Pei W, Xu L, Huang S, Pettie K, Idol J, Rissone A, et al.
NPJ Regen Med
. 2018 Jun;
3:11.
PMID: 29872546
Regenerative medicine holds great promise for both degenerative diseases and traumatic tissue injury which represent significant challenges to the health care system. Hearing loss, which affects hundreds of millions of...