Wouter Koudstaal
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Explore the profile of Wouter Koudstaal including associated specialties, affiliations and a list of published articles.
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33
Citations
2875
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Recent Articles
1.
Beukenhorst A, Frallicciardi J, Rice K, Koldijk M, Moreira de Mello J, Klap J, et al.
Sci Rep
. 2024 Feb;
14(1):3818.
PMID: 38360813
Avian A(H5N1) influenza virus poses an elevated zoonotic threat to humans, and no pharmacological products are currently registered for fast-acting pre-exposure protection in case of spillover leading to a pandemic....
2.
Roozendaal R, Solforosi L, Stieh D, Serroyen J, Straetemans R, Dari A, et al.
Nat Commun
. 2021 Oct;
12(1):5877.
PMID: 34620860
Several COVID-19 vaccines have recently gained authorization for emergency use. Limited knowledge on duration of immunity and efficacy of these vaccines is currently available. Data on other coronaviruses after natural...
3.
Wu J, Yaqub A, Ma Y, Koudstaal W, Hofman A, Ikram M, et al.
Sci Rep
. 2021 Aug;
11(1):15929.
PMID: 34354164
Application of biological age as a measure of an individual´s health status offers new perspectives into extension of both lifespan and healthspan. While algorithms predicting mortality and most aging-related morbidities...
4.
Goudsmit J, van den Biggelaar A, Koudstaal W, Hofman A, Koff W, Schenkelberg T, et al.
Eur J Epidemiol
. 2021 Jun;
36(7):753-762.
PMID: 34117979
The Human Immunomics Initiative (HII), a joint project between the Harvard T.H. Chan School of Public Health and the Human Vaccines Project (HVP), focuses on studying immunity and the predictability...
5.
de Wolf F, Ghanbari M, Licher S, McRae-McKee K, Gras L, Weverling G, et al.
Brain
. 2020 Mar;
143(4):1220-1232.
PMID: 32206776
CSF biomarkers, including total-tau, neurofilament light chain (NfL) and amyloid-β, are increasingly being used to define and stage Alzheimer's disease. These biomarkers can be measured more quickly and less invasively...
6.
Perry S, Keogh E, Morton M, Koudstaal W, Pascual G
J Vis Exp
. 2019 Sep;
(150).
PMID: 31498318
The human antibody repertoire represents a largely untapped source of potential therapeutic antibodies and useful biomarkers. While current computational methods, such as next generation sequencing (NGS), yield enormous sets of...
7.
Puchades C, Kukrer B, Diefenbach O, Sneekes-Vriese E, Juraszek J, Koudstaal W, et al.
Sci Rep
. 2019 Mar;
9(1):4735.
PMID: 30894620
Epitope characterization is critical for elucidating the mechanism of action of drug candidates. However, traditional high-resolution epitope mapping techniques are not well suited for screening numerous drug candidates recognizing a...
8.
van Dongen M, Kadam R, Juraszek J, Lawson E, Brandenburg B, Schmitz F, et al.
Science
. 2019 Mar;
363(6431).
PMID: 30846569
Recent characterization of broadly neutralizing antibodies (bnAbs) against influenza virus identified the conserved hemagglutinin (HA) stem as a target for development of universal vaccines and therapeutics. Although several stem bnAbs...
9.
Li X, Koudstaal W, Fletcher L, Costa M, van Winsen M, Siregar B, et al.
Acta Neuropathol
. 2019 Feb;
137(5):825-836.
PMID: 30805666
Deposition of α-synuclein into Lewy bodies and Lewy neurites is the hallmark of Parkinson's disease (PD). It is hypothesized that α-synuclein pathology spreads by a "prion-like" mechanism (i.e., by seeded...
10.
Crespo R, Koudstaal W, Apetri A
J Vis Exp
. 2018 Dec;
(141).
PMID: 30531722
Aggregation of tau protein and formation of paired helical filaments is a hallmark of Alzheimer's disease and other tauopathies. Compared to other proteins associated with neurodegenerative diseases, the reported in...